响应面法优化超声乙醇提取南五味子藤茎中木脂素工艺  

Optimization of the ultrasonic ethanol extraction process of lignans from the cane of Schisandra chinensis(Turcz.)Baill.by the response surface methodology

作　　者：穆开朗 程昆木 王锦 陈嘉悦 MU Kai-lang;CHENG Kun-mu;WANG Jin;CHEN Jia-yue(School of Chemistry and Chemical Engineering,Ankang University,Ankang 725000,Shaanxi,China;Qinba Traditional Chinese Medicine Resources Research and Development Center,Ankang University,Ankang 725000,Shaanxi,China)

机构地区：[1]安康学院化学化工学院,陕西安康725000 [2]安康学院秦巴中药资源研发中心,陕西安康725000

出　　处：《湖北农业科学》2022年第8期109-114,162,共7页Hubei Agricultural Sciences

基　　金：陕西省教育厅项目(18JK0021)。

摘　　要：采用超声-乙醇法提取南五味子[Schisandra chinensis(Turcz.)Baill.]藤茎中的木脂素,并以超声功率、超声时间、超声温度和料液比作为考察因素,将南五味子藤茎木脂素的提取率作为响应值,在单因素试验的基础上,采用响应面Box-Behnken设计并优化试验方案。结果表明,响应面法优化试验的最优条件为超声功率160 W,超声时间50 min,超声温度55℃,料液比1∶27(g/mL),在此条件下提取率为0.371%。说明响应面法可以较好地优化超声-乙醇提取南五味子藤茎中木脂素的工艺条件,同时为工业化开发利用五味子藤茎以及中药材废弃部位的应用提供理论依据。The lignans in the cane of Schisandra chinensis(Turcz.)Baill.were extracted by the ultrasonic-ethanol method,and the ul⁃trasonic power,ultrasonic time,ultrasonic temperature and material-liquid ratio were taken as investigation factors,and the extrac⁃tion rate of lignans from the cane of Schisandra chinensis(Turcz.)Baill.was used as the response value,based on the single factor ex⁃periment,the response surface Box-Behnken was used to design and optimize the experimental plan.The results showed that the opti⁃mal conditions for the response surface methodology optimization experiment were the ultrasonic power 160 W,ultrasonic time 50 min,ultrasonic temperature 55℃,material-liquid ratio 1∶27(g/mL),the extraction rate was 0.371%under this condition.It showed that the response surface methodology can better optimize the ultrasonic-ethanol extraction of lignans from the cane of Schisandra chinensis(Turcz.)Baill.,and provide the theoretical basis for the industrial development and utilization of the cane of Schisandra chinensis(Turcz.)Baill.and the application of waste parts of Chinese medicinal materials.

关 键 词：南五味子[Schisandra chinensis(Turcz.)Baill.] 藤茎 木脂素 提取率 响应面法 

分 类 号：R284.2[医药卫生—中药学]