黛力新联合管石复位对合并焦虑抑郁的良性阵发性位置性眩晕的疗效分析  

Effect of Deanxit Combined with Canalith Repositioning on Benign Paroxysmal Positional Vertigo Patients with Anxiety and Depression

作　　者：刘丹[1] 徐芬[1] 万浪[1] 彭聪[1] 喻辉 Liu Dan;Xu Fen;Wan Lang;Peng Cong;Yu Hui(Department of Otorhinolaryngology,Huangshi Central Hospital of Edong Healthcare Group,Hubei Polytechnic University,Huangshi,435000,China)

机构地区：[1]鄂东医疗集团黄石市中心医院(湖北理工学院附属医院)耳鼻喉科,黄石435000

出　　处：《听力学及言语疾病杂志》2022年第3期248-252,共5页Journal of Audiology and Speech Pathology

摘　　要：目的探讨黛力新联合管石复位(canalith repositioning,CRP)在合并焦虑抑郁的良性阵发性位置性眩晕患者(benign paroxysmal positional vertigo,BPPV)不同阶段的疗效。方法回顾性分析2016年1月~2020年12月收治的360例伴焦虑及抑郁的BPPV患者,根据不同的治疗方法分成A组常规组、A组联合组、B组常规组、B组联合组4组,每组90例,A组常规组给予患者敏使朗药物治疗(每次6 mg,每日3次)后再行CRP治疗,疗程7天;B组常规组先行CRP治疗后再同法给予敏使朗治疗,两组联合组均在两组常规组口服敏使朗同时口服黛力新(每日1次,每次1片,疗程3个月)。比较4组患者的首次CRP舒适度评分、DHI量表评分、焦虑状态量表(self-rating anxiety scale,SAS)、抑郁状态量表(self-rating depression scale,SDS)评分,治疗3个月后残余头晕的发作比例、持续时间、CRP治疗的总次数以及BPPV的治愈率和复发率。结果A组联合组首次复位舒适度(visual analogue scale,VAS)评分优于其他三组;治疗1周后,B组联合组DHI评分、SAS、SDS评分优于另外三组,另外三组两两比较均有统计学差异;治疗1月后和3个月时,A组联合组优于另外三组,另外三组两两比较均有统计学差异(P<0.05)。治疗3个月后,A组联合组残余头晕的发作比例少于另外三组,A组联合组和B组联合组CRP的总次数和复发率小于另外两组,差异有统计学意义(P<0.05);B组联合组头晕持续时间少于另外三组,B组常规组小于A组两组,A组联合组头晕持续时间短于A组常规组,差异有统计学意义(P<0.05)。治疗1周后,B组常规组和联合组治愈率高于A组常规组和联合组;治疗1月和3月后,A组联合组和B组联合组治愈率高于另外两组,差异均有统计学意义(P<0.05)。结论对于伴焦虑和抑郁的BPPV患者,应用基础药物联合黛力新治疗后再行CRP治疗能够进一步改善患者的临床症状和精神状态,提高治愈率,降低残余头晕的发生比例。Objective To investigate the efficacy of deanxit combined with canalith repositioning(CRP)in different stages of benign paroxysmal positional vertigo(BPPV)patients with anxiety and depression.Methods Retrospective analysis of 360 BPPV patients with anxiety and depression treated from Jan 2016 to Dec 2020 were randomly divided into 4 groups according to different treatment methods.The convention group of group A was treated with betastatin(6 mg each time,3 times a day)for 7 days before the CRP,the convention group of group B was treated with betastatin after CRP.The usage,dosage and course of treatment of group B were the same as that of group A.The two combined groups were given deanxit(once a day,one tablet each time,for 3 months)on the basis treatment of convention group.The first CRP comfort score,DHI scale score,self-rating anxiety scale(SAS),self-rating depression scale(SDS)score,incidence rate of residual dizziness,duration of CRP,total number of CRP and recurrence rate and cure rate of BPPV were compared among the four groups.Results The VAS score of the first reduction comfort in conventional group A was better than that in the other three groups.After one week of treatment,DHI score,SAS and SDS score of group B combined group were better than those of the other three groups,and there were significant differences between the other three groups.After 1 month and 3 months of treatment,group A combined group was better than the other three groups,and there was significant difference between the other three groups(P<0.05).After 3 months of treatment,the incidence of residual dizziness in combined group A was less than that in the other three groups.The frequency and recurrence rate of CRP in combined group A and combined group B were less than those in the other two groups.The duration of halos was shorter than that in group A.After 1 week of treatment,the cure rate of conventional and combined group B were higher than that of two group A.After 1 and 3 months of treatment,the cure rate of combined group A and

关 键 词：良性阵发性位置性眩晕 焦虑 抑郁 残余头晕 

分 类 号：R764.34[医药卫生—耳鼻咽喉科]