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作 者:张之奎 林士婷 张宝华[2] 史兰香[2] Zhang Zhikui;Lin Shiting;Zhang Baohua;Shi Lanxiang(Shijiazhuang Penghai Pharmacutical co Itd,Hebei 050600;College of Chemical Engineering,Shijiazhuang University,Hebei 050035)
机构地区:[1]石家庄鹏海制药股份有限公司,河北050600 [2]石家庄学院化工学院,河北050035
出 处:《天津药学》2022年第2期5-7,21,共4页Tianjin Pharmacy
基 金:河北省科技小巨人计划项目(No.18C1303111026);河北省科技支撑项目(No.20322601D)。
摘 要:目的:以聚乙二醇多氢键功能化合物为改性剂制备改性聚醚砜滤芯,增加滤芯水通量,增加滤芯去除药液中重金属的功能。方法:用改性剂改性聚醚砜,用熔融共混法制备了改性材料和改性滤芯。结果:改性聚醚砜滤芯水通量可达到96.03 L/(m^(2)·h),改性滤芯循环使用批次可达到50批,寿命大大延长。结论:改性聚醚砜滤芯水通量高,能有效截留注射液中的重金属离子,能再生循环使用,生产成本低。Objective:To prepare modified polyethersulfone filter element with polyethylene glycol multi-hydrogen bond functional compound as modifier,to increase the water flux of the filter element and its ability to remove heavy metals from the drug solution.Methods:Polyethersulfone was modified by modifying agent,and the modified material and filter element were prepared by melt blending method.Results:The water flux of the modified polyethersulfone filter element can reach 96.03 L/(m^(2)·h^(-1)).The circulating batch of the modified polyethersulfone filter element can reach 50 batches,and the service life of the modified filter element is greatly increased.Conclusion:The modified polyethersulfone filter element has high water flux and can effectively intercept heavy metal ions in injection.Can be recycled,low production cost.
关 键 词:聚乙二醇多氢键功能化合物 聚醚砜 改性滤芯 盐酸氨溴索葡萄糖注射液
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