WHOQOL-BREF用于评价HIV感染者生活质量的信、效度研究  

Assessment on the validity and reliability of the WHOQOL-BREF among HIV cases

作　　者：徐迪 端琼丽 潘玲 黄能梅 韩晶[1] 李健[1] XU Di;DUAN Qiong-li;PAN Ling;HUANG Neng-mei;HAN Jing;LI Jian(National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Department of AIDS Control and Prevention,Center for Disease Control and Prevention of Hani-Yi Autonomous Prefecture of Honghe,Mengzi 661199,China)

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [2]红河哈尼族彝族自治州疾病预防控制中心艾滋病防制科,蒙自661199

出　　处：《中华疾病控制杂志》2022年第5期576-582,共7页Chinese Journal of Disease Control & Prevention

基　　金：中国疾病预防控制中心性病艾滋病预防控制中心青年科研基金(2018AFQN004)。

摘　　要：目的评价世界卫生组织生活质量测定简表(World Health Organization quality of life scale-brief form questionnaire,WHOQOL-BREF)在测定HIV感染者生活质量中应用的信度和效度,比较不同特征HIV感染者的生活质量,为下一步评价感染者的生活质量和制定有效的关怀措施提供参考依据。方法采用方便抽样的方法在云南省红河哈尼族彝族自治州选择符合条件的HIV感染者。采用Cronbach’sα系数和分半信度评价其信度;探索性因子分析(exploratory factor analysis,EFA)和验证性因子分析(confirmatory factor analysis,CFA)检验其效度;单因素方差分析比较不同特征感染者在WHOQOL-BREF各维度上的得分情况。结果共获得410份有效问卷。WHOQOL-BREF及生理领域、心理领域、社会领域和环境领域的Cronbach’sα系数分别为0.901、0.779、0.819、0.729和0.743,分半信度分别为0.798、0.716、0.822、0.736和0.697。EFA共获取4个公因子,对总体方差的贡献率为54.542%;CFA结果显示最终拟合模型的主要指标χ^(2)/df和估计误差均方根(root-mean-square error of approximation,RMSEA)分别为2.169和0.076;拟合优度模型指数(goodness of fit index,GFI)、比较拟合指数(comparative fit index,CFI)和Tucker-Lewis指数(Tucker-Lewis index,TLI)分别为0.820、0.861和0.844,均接近0.900,表示拟合结果可以接受。单因素方差分析结果显示,是否接受抗逆转录病毒治疗、民族、职业、文化程度和最近一次CD4^(+)T淋巴细胞计数等不同特征感染者的生活质量有所不同。结论WHOQOL-BREF在测定HIV感染者的生活质量具有较好的信度和效度,不同特征感染者的生活质量有所差异,在制定有针对性的干预策略和措施时需加以考虑。Objective The objective of the study was to assess the reliability and validity of the World Health Organization quality of life scale-brief form questionnaire(WHOQOL-BREF)and compare the quality of life among HIV cases,providing a basis for evaluating the quality of life and formulating effective measures of HIV cases.Methods HIV cases were recruited through convenience sampling method in Honghe Hani-Yi Autonomous Prefecture,Yunnan Province.Reliability was assessed by using Cronbach'sαand split-half reliability,while exploratory factor analysis(EFA)and confirmatory factor analysis(CFA)were used to assess its validity.ANOVA were used to compare the scores of different characteristics.Results A total of 410 valid questionnaires were obtained.Cronbach'sαof WHOQOL-BREF and physical,psychological,social relationships,environment of WHOQOL-BREF were 0.901,0.779,0.819,0.729,0.743 respectively.The related correlation coefficients of split half were 0.798,0.716,0.822,0.736,0.697 respectively.Exploratory factor analysis obtained four communal factors,with a contribution of 54.542%to the overall variance.The results of the confirmatory factor analysis showed that the main indicators of the fitted model wereχ^(2)/df and the root-mean-square error of approximation(RMSEA),and the value were 2.169 and 0.076 respectively.Goodness of fit index(GFI),comparative fit index(CFI)and Tucker-Lewis index(TLI)were 0.820,0.861 and 0.844 respectively.All value were closed to 0.900,indicating an accepted level.ANOVA results showed that there were different quality of life among HIV cases with different characteristics such as receiving antiretroviral therapy or not,ethnicity,occupation,education and last CD4^(+)T lymphocyte count.Conclusion The reliability and validity of the WHOQOL-BREF are good,and quality of life varied by different characteristics of HIV cases prompting the intervention strategies pertinently.

关 键 词：HIV 生活质量 世界卫生组织生活质量测定简表 

分 类 号：R512.91[医药卫生—内科学]