Application of Langlois' reagent(NaSO_(2)CF_(3)) in C–H functionalisation  

作　　者：Jiabin Shen Jun Xu Lei He Chenfeng Liang Wanmei Li 

机构地区：[1]College of Material,Chemistry and Chemical Engineering,Key Laboratory of Organosilicon Chemistry and Material Technology,Ministry of Education,Hangzhou Normal University,Hangzhou 311121,China

出　　处：《Chinese Chemical Letters》2022年第3期1227-1235,共9页中国化学快报（英文版）

基　　金：Natural Science Foundation of Zhejiang Province(No. LY21B060009) for financial support。

摘　　要：The process of selectively introducing a CF_(3) group into an organic molecule using inexpensive, stable, and solid sodium trifluoromethanesulfinate has rapidly advanced in recent years to become an eco-friendly method used by organic chemists to synthesize various natural and bioactive molecules. This review focuses on advances made within the last five years regarding C-H functionalisation, namely thermochemical C(sp^(2))-H (thio)trifluoromethylations, photochemical C(sp^(2))-H trifluoromethylations, and electrochemical C(sp^(2))-H trifluoromethylations, using Langlois’ reagent (NaSO_(2)CF_(3)).

关 键 词：TRIFLUOROMETHYLATION Langlois’reagent Reaction mechanism Synthetic method C–H activation 

分 类 号：O621.25[理学—有机化学]