Quantum dots-hydrogel composites for biomedical applications  

作　　者：Wenjie Zhou Zhe Hu Jinxin Wei Hanqing Dai Yuanyuan Chen Siyu Liu Zhongtao Duan Fengxian Xie Wanlu Zhang Ruiqian Guo 

机构地区：[1]Institute for Electric Light Sources,School of Information Science and Technology,Fudan University,Shanghai 200433,China [2]Institute of Future Lighting,Academy for Engineering and Technology,Fudan University,Shanghai 200433,China [3]Zhongshan-Fudan Joint Innovation Center,Zhongshan 528437,China [4]Yiwu Research Institute of Fudan University,Yiwu 322000,China

出　　处：《Chinese Chemical Letters》2022年第3期1245-1253,共9页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China (NSFC, Nos. 62074044, 61904036 and 61675049);Zhongshan-Fudan Joint Innovation Center and Jihua Laboratory Projects of Guangdong Province (No. X190111UZ190)。

摘　　要：Quantum dots-hydrogel composites are promising new materials that have attracted extensive attention due to their incomparable biocompatibility and acceptable biodegradability, leading to enormous potential applications for various fields. This review summarizes the recent advances in quantum dots-hydrogel composites with a focus on synthesis methods, including hydrogel gelation in quantum dots(QDs) solution, embedding prepared QDs into hydrogels after gelation, forming QDs in situ within the preformed gel and cross-linking via QDs to form hydrogels. In particularly, biomedical applications as bioimaging,biosensing and drug delivery are also reviewed, followed by a discussion on the inherent challenges of design optimization, biocompatibility and bimodal applications and the prospect of the future development. These results will guide the development of quantum dots-hydrogel composites and provide critical insights to inspire researchers in future.

关 键 词：Quantum dots HYDROGELS BIOIMAGING BIOSENSING Drug delivery 

分 类 号：R318.08[医药卫生—生物医学工程] TQ427.26[医药卫生—基础医学] TB332[化学工程]