呼和浩特地区非创伤性股骨头坏死中医体质类型调查研究  

Investigation into TCM Constitutions of Patients with Nontraumatic Osteonecrosis of Femoral Head in Hohhot Region

作　　者：赵军 师建平 ZHAO Jun;SHI Jianping(Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine,Hohehot 010020,China;TCM College,Inner Mongolia Medical University)

机构地区：[1]内蒙古自治区中医医院,内蒙古呼和浩特010020 [2]内蒙古医科大学中医学院

出　　处：《西部中医药》2022年第5期100-104,共5页Western Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(30560165);国家中医药管理局中医药传承与创新“百千万人才工程”项目(J20184832009);第四批全国中医(临床、基础)优秀人才研修项目(J20184832009);内蒙古自治区自然科学基金(2009MS1134);内蒙古医科大学“科技百万工程”联合项目[YKD2017KJBW(LH)064];内蒙古自治区第三批老蒙医药中医药专家学术经验继承项目(内卫计蒙中字[2019]126);内蒙古自治区草原英才创新团队“中医治未病”项目(CYYCTD2018);内蒙古自治区“321人才工程”第一层次人选。

摘　　要：目的:调查呼和浩特地区非创伤性股骨头坏死(nontraumatic osteonecrosis of femoral head,NONFH)患者的中医体质分布特点,为体质与疾病相关理论提供流行病学依据。方法:筛选呼和浩特地区NONFH患者179例作为病例组,进行中医体质类型问卷调查,判定其体质类型,并随机选取309例非血缘关系健康志愿者为对照组。中医体质调查采用标准化的中医体质量表,体质类型判定按照《中医体质分类与判定》标准进行。采用多元逐步Logistic回归分析筛选NONFH有意义的主要体质影响因素。结果:发病因素相关性:病例组与对照组在年龄、体质指数(body mass index,BMI)等方面均存在明显差异(P<0.05)。两组性别比较差异无统计学意义(P>0.05)。体质分布特点:气虚质、痰湿质、湿热质、血瘀质、气郁质频率病例组高于对照组,差异有统计学意义(P<0.05);平和质频率病例组低于对照组(P<0.05),两组阳虚质、阴虚质、特禀质频率比较差异无统计学意义(P>0.05)。男性(OR=3.015,95%CI[1.516,5.996]、年龄(OR=1.092,95%CI[1.065,1.119])及气虚质(OR=3.541,95%CI[1.111,11.285])、痰湿质(OR=30.208,95%CI[4.263,214.047])、血瘀质(OR=18.678,95%CI[4.620,75.510])为NONFH的独立危险因素。结论:在呼和浩特地区,男性、年龄为NONFH的独立危险因素,气虚质、痰湿质、血瘀质为NONFH的高发体质类型,亦是NONFH的独立危险因素。Objective:To survey the distribution characteristics of TCM constitutions of NONFH patients in Hohhot region,in a bid to provide epidemiological basis for the constitutions and disease-related theory.Methods:All 179 NONFH patients in Hohhot region were chosen as the case group,and surveyed with the questionnaire on constitution types of TCM,to judge the patients’ constitutions,another 309 unrelated healthy volunteers were randomly selected as the control group,the TCM constitution survey adopts the standardized TCM body mass table,and the constitution type is determined according to the standard of TCM constitution classification and determination.Multiple stepwise logistic regression analysis was used to screen the main physical influencing factors of NONFH.Results:Correlation of pathogenic factors:the significant difference existed in age,BMI between the case group and the control group(P<0.05).The difference had no statistical meaning in gender between both groups(P>0.05).Physical distribution characteristics:the case group was higher than the control group in the frequency of the constitutions of Qi deficiency constitution,phlegm-damp,damp-heat,blood stasis,Qi stagnation,and the difference was statistically significant(P<0.05);the case group was lower than the control group in the frequency of normal constitution(P<0.05);the difference had no statistical meaning in Yang deficiency constitution,Yin deficiency constitution and special constitution between both groups(P>0.05).Male(OR=3.015;95%CI[1.516-5.996]),age(OR=1.092;95%CI[1.065-1.119]) and Qi deficiency constitution(OR=3.541;95%CI[1.111-11.285),phlegm damp constitution(OR=30.208;95%CI[4.263-214.047]) and blood stasis constitution(OR=18.678;95%CI[4.620-75.510]) are the independent risk factors of NONFH.Conclusion:In Hohhot region,male and age are the independent risk factors of NONFH,Qi deficiency constitution,phlegm damp constitution and blood stasis constitution show high incidence to NONFH,and they are also the independent risk factors of NONFH.

关 键 词：非创伤性股骨头坏死 中医体质类型 流行病学 危险因素 呼和浩特地区 

分 类 号：R274[医药卫生—中医骨伤科学]