硫酸吗啡缓释片联合针灸对癌痛患者镇痛效果及生存质量的影响  

Analysis of the analgesic effect and quality of life in cancer patients who receiving morphine sulfate sustained-release tablets combined with acupuncture

作　　者：李非铭 赵俊莺 方海博 舒雅[1] LI Feiming;ZHAO Junying;FANG Haibo;SHU Ya(Department of Pain Treatment,the First Affiliated Hospital of Xi'an Medical College,Xi'an 710077,China;不详)

机构地区：[1]西安医学院第一附属医院疼痛科,西安710077

出　　处：《实用医学杂志》2022年第6期763-766,共4页The Journal of Practical Medicine

摘　　要：目的 观察硫酸吗啡缓释片联合针灸治疗癌症疼痛患者的临床效果。方法 选取2020年1月至2021年6月在我院收治的癌痛患者70例,随机分为对照组和观察组,每组35例。对照组采用硫酸吗啡缓释片治疗,观察组在对照组治疗基础上采用针灸治疗足三里、百会穴、阿是穴。治疗14 d后采用NRS,KPS对患者疼痛情况和生存质量进行评价,并分析治疗后每日药物使用量以及疼痛缓解率和不良反应发生率。结果 观察组患者总有效率为91.43%,高于对照组82.86%(Z=12.120,P=0.007),治疗后观察组患者较对照组NRS评分降低,KPS评分升高(P <0.05)。与治疗前相比,观察组患者硫酸吗啡缓释片日用量基本维持,而对照组患者药物使用量显著增加。不良反应发生率观察组为48.57%,对照组为77.14%。结论 针灸联合硫酸吗啡缓释片缓解癌痛,提高患者生存质量,降低不良反应发生率,安全性高,值得临床推广。Objective The study aimed to observe the clinical effect of morphine sulfate sustained-release tablets combined with acupuncture on cancer pain.Methods A total of seventy patients with cancer pain admitted to our hospital from January 2020 to June 2021 were randomly divided into control group and observation group.There were 35 cases in each group respectively.The control group was treated with morphine sulfate sustainedrelease tablets and the observation group with acupuncture and moxibustion at Zusanli,Baihui and Ashi points.NRS and KPS were applied to evaluate the pain and quality of life.The daily drug use,pain relief rate and incidence of adverse reactions after treatment were analyzed.Results The effective rate in observation group was 91.43%,which was higher than 82.86%in control group(Z=12.120,P=0.007).After treatment,the NRS score and KPS score in observation group were lower than those in control group(P<0.05).Compared with the data before treatment,the daily dosage of morphine sulfate sustained-release tablets in the observation group was basically maintained,while the dosage of drugs in the control group was significantly increased.The incidence of adverse reactions was 48.57%in observation group and 77.14%in control group.ConclusionAcupuncture and moxibustion combined with morphine sulfate sustained-release tablets could relieve cancer pain,improve the quality of life of patients,reduce the incidence of adverse reactions and had high safety,which was worthy of clinical promotion.

关 键 词：癌痛 硫酸吗啡缓释片 针灸 镇痛 

分 类 号：R273[医药卫生—中西医结合]