广东省妊娠合并糖尿病流行状况调查  

The prevalence of pregnancy with diabetes mellitus in Guangdong province

作　　者：陈晓玲 缪华章[2] 曹筱佩[3] 曾静[1,2] 李荔[1] CHEN Xiaoling;MIAO Huazhang;CAO Xiaopei;ZENG Jing;LI Li(Guangdong Pharmaceutical University,Guangzhou 510006,China;不详)

机构地区：[1]广东药科大学,广州510006 [2]广东省妇幼保健院,广州511400 [3]中山大学附属第一医院,广州510080

出　　处：《实用医学杂志》2022年第7期909-912,共4页The Journal of Practical Medicine

基　　金：广东省自然科学基金(编号:2021A1515010763);广东省国际及港澳台高端人才交流专项(海外名师-团体类项目)(编号:174007);2021年度澳门特别行政区科学技术发展基金(编号:0048/2021/A1);2019年广州市科技计划科学研究专项(编号:201904010458)。

摘　　要：目的 了解广东省妊娠合并糖尿病流行现状,为广东省妊娠合并糖尿病防控提供依据。方法 收集2016-2020年广东省21个地市2 440所医疗机构所报告的产科质量报表,分析广东省妊娠合并糖尿病的流行现状及其与妊娠不良结局(剖宫产、早产儿、围产儿死亡)的相关性。结果 研究期间共监测产妇8 553 069例,报告妊娠合并糖尿病患者639 637例,患病率为7.48%。2016-2020年全省患病率呈线性递增趋势,差异有统计学意义(χ2=35 738.01,P <0.001)。广东省21个地市中佛山市患病率最高,为14.20%;揭阳市最低,为0.45%。按行政区域划分,珠江三角患病率最高,为10.53%;粤西最低,为2.84%,不同行政区域患病率差异有统计学意义(P <0.05)。按医院分级划分,三级医院患病率最高,为11.08%;一级医院最低,为2.22%,不同医院级别患病率差异均有统计学意义(P <0.05)。在妊娠合并糖尿病与妊娠不良结局的相关性分析中,妊娠合并糖尿病人数与剖宫产人数、早产儿人数及围产儿死亡人数呈正相关(P <0.05)。结论 2016-2020年期间广东省妊娠合并糖尿病患病率显著增加,有明显的地区差异性,且与不良妊娠结局呈正相关。Objective To analyze the prevalence of pregnancy with diabetes mellitus and provide evidence for the prevention and control of pregnancy with diabetes mellitus in Guangdong Province.Methods Based on an obstetric quality report from 2 440 medical institutions in 21 cities of Guangdong province from 2016 to 2020,we analyzed the current status of prevalence of gestational diabetes mellitus in Guangdong and the relationship between gestational diabetes mellitus and adverse pregnancy outcomes including cesarean section,premature infants,perinatal death.Results During the study period,a total of 8 553 069 pregnant women were monitored,and639 637 of them were reported as having pregnancy with diabetes,with a prevalence rate of 7.48% in Guangdong.The prevalence of pregnancy with diabetes mellitus from 2016 to 2020 showed a trend of linear growth,and it was statistically significant(χ2= 35 738.01,P < 0.001).Among all the cities,Foshan had the highest prevalence rate of14.20 %,while Jieyang had the lowest rate of 0.45%;Division by administrative regions,the Pearl River Triangle area had the highest rate of 10.53%,whereas Yuexi had the lowest rate of 2.84%.There were significant differences in the prevalence rate among different administrative regions(P < 0.05).Division by medical institutions,the thirdlevel hospitals had the highest rate of 11.08%,while the first-level hospitals had the lowest rate of 2.22%.There were significant differences in the prevalence rate among different medical institutions(P < 0.05).In the correlation analysis on pregnancy with diabetes mellitus and adverse pregnancy outcomes,pregnancy complicated with diabetes was positively correlated with Cesarean section,premature infants and perinatal death(P < 0.05).Conclusions During the period of 2016 to 2020,the prevalence of pregnancy with diabetes in Guangdong province increased significantly,with a significant regional difference.The disorder was positively correlated with adverse pregnancy outcomes.

关 键 词：妊娠合并糖尿病 患病率 流行状况 

分 类 号：R714.256[医药卫生—妇产科学]