MR多模态成像诊断皮层下区胶质母细胞瘤与单发颅脑转移瘤的价值分析  

The value analysis of MR multimodal imaging in the diagnosis of subcortical glioblastoma and single brain metastases

作　　者：李欣[1] 王冬女[1] 谢继承[1] 吴玲 张黄琦 董雪 Li Xin

机构地区：[1]浙江省台州医院,317000

出　　处：《浙江临床医学》2022年第4期490-492,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省医药卫生科技计划项目(2019KY777);台州市科技计划项目(1902ky30)。

摘　　要：目的探讨MRS、ADC及SWI磁共振多模态成像在皮层下区胶质母细胞与单发颅脑转移瘤中的诊断价值。方法收集经手术或活检病理证实的累及皮层或皮层下胶质母细胞瘤35例、单发颅脑转移瘤31例,术前均行常规MR平扫+增强、MRS、DWI及SWI检查,对照分析两组的影像学检查结果。结果胶质母细胞瘤实体区的Cho/NAA显著高于脑转移瘤,差异有统计学意义(P<0.05)。胶质母细胞瘤瘤周水肿的Cho/Cr、Cho/NAA显著高于脑转移瘤,差异有统计学意义(P<0.05)。胶质母细胞瘤与单发颅脑转移瘤实质部分ADC值比较,差异无统计学意义(P>0.05)。肿瘤周围水肿带的ADC值比较,差异有统计学意义(P<0.05)。SWI提示两种肿瘤的出血个数、ITSS评分无统计学意义(P>0.05),但胶质母细胞瘤增生血管个数显著高于脑转移瘤(P<0.05)。结论MRS、ADC及SWI多模态成像对胶质母细胞瘤与转移瘤的鉴别诊断及肿瘤侵犯范围评估具有重要应用价值。Objective To investigate the diagnosis value of MRS,ADC and SWI multimodal imaging of subcortical glioblastoma and single brain metastases.Methods 35 cases of glioblastoma involving cortex or subcortex and 31 cases of single metastatic tumor confirmed by surgery or biopsy were collected.Unenhanced and enhanced MRS、DWI、SWI preoperative MR examinations were routinely performed for all tumors,and the results of the two groups were compared.Results Cho/NAA in the solid area of glioblastoma was significantly higher than that in brain metastases,with statistical significance(P<0.05).Cho/Cr and Cho/NAA of peritumoral edema in glioblastoma were significantly higher than those in brain metastases,with statistical significance(P<0.05).There was no significant difference in ADC value between glioblastoma and single metastatic tumor(P>0.05).There was significant difference in ADC value of edema zone around tumor(P<0.05).SWI showed that the number of bleeding and ITSS score of the two tumors were not statistically significant(P>0.05),but the number of proliferative vessels in glioblastoma was significantly higher than that in brain metastases(P<0.05).Conclusion MRS,ADC and SWI multimodal imaging have important application value in the differential diagnosis of glioblastoma and single metastatic tumor,and the evaluation of tumor invasion.

关 键 词：磁共振波普学 表观弥散系数 磁敏感加权成像 胶质母细胞瘤 单发颅脑 转移瘤 

分 类 号：R44[医药卫生—诊断学]