A Hybrid Immersed Boundary/Coarse-Graining Method for Modeling Inextensible Semi-Flexible Filaments in Thermally Fluctuating Fluids Dedicated to Professor Karl Stark Pister for his 95th birthday  

作　　者：Magdalini Ntetsika Panayiotis Papadopoulos 

机构地区：[1]Department of Mechanical Engineering,University of California,Berkeley,CA,94720-1740,USA

出　　处：《Computer Modeling in Engineering & Sciences》2021年第12期1243-1258,共16页工程与科学中的计算机建模（英文）

摘　　要：A new and computationally efficient version of the immersed boundary method,which is combined with the coarse-graining method,is introduced for modeling inextensible filaments immersed in low-Reynolds number flows.This is used to represent actin biopolymers,which are constituent elements of the cytoskeleton,a complex network-like structure that plays a fundamental role in shape morphology.An extension of the traditional immersed boundary method to include a stochastic stress tensor is also proposed in order to model the thermal fluctuations in the fluid at smaller scales.By way of validation,the response of a single,massless,inextensible semiflexible filament immersed in a thermally fluctuating fluid is obtained using the suggested numerical scheme and the resulting time-averaged contraction of the filament is compared to the theoretical value obtained from the worm-like chain model.

关 键 词：Semiflexible biopolymers immersed boundary method COARSE-GRAINING actin filaments fluid-structure interaction thermal fluctuations persistence length 

分 类 号：O17[理学—数学]