表面增强拉曼光谱与其他检测技术联用的概述  

Overview of surface-enhanced Raman spectroscopy in combination with other detection techniques

作　　者：崔晓林 桂玲 朱茜 陆峰 CUI Xiaolin;GUI Ling;ZHU Qian;LU Feng(No.63680 Hospital of the PLA,Jiangyin 214400,China;Department of Pharmaceutical Analysis,School of Pharmacy,Naval Medical University,Shanghai 200433,China)

机构地区：[1]中国人民解放军63680部队医院,江苏江阴214400 [2]海军军医大学药学系药物分析教研室,上海200433

出　　处：《药学实践杂志》2022年第3期202-207,253,共7页Journal of Pharmaceutical Practice

基　　金：上海市军民融合发展专项(2020-jmrh1-kj11)。

摘　　要：表面增强拉曼光谱(SERS)作为日渐成熟的分析检测技术,对自然界中许多单一物质具有鉴别检测,甚至是定量测定的能力。但在实际样品分析中,被测样品往往是多种物质的混合体系,单纯依靠SERS技术无法实现对混合体系各组成成分的准确表征。因此,SERS联用其他技术手段来对被测物质进行准确测定已成为必然趋势。通过联用的方式,提高SERS在检测和表征方面的不足,实现高效、灵敏、准确地测定被测物质的目的。As an increasingly mature analytical technique,surface-enhanced Raman spectroscopy has the ability to identify,detect,and even quantitatively measure many single substances in nature.However,in the actual sample analysis,the tested samples were often a mixed system of various substances,and it was impossible to accurately characterize the components of the mixed system only by relying on SERS technology.Therefore,SERS combined with other techniques to accurately determine the measured substances has become an inevitable trend.Through the combination,the deficiency of SERS in detection and characterization was improved,and the purpose of efficient,sensitive and accurate determination of substances to be measured was achieved.

关 键 词：表面增强拉曼散射光谱 联用 分析测定 

分 类 号：R917[医药卫生—药物分析学]