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作 者:赵静 吴秀清[1] ZHAO Jing;WU Xiu-Qing(Internal Medicine,Shenyang children's Hospital,Shenyang 110032,China)
出 处:《中国药物经济学》2022年第3期66-68,72,共4页China Journal of Pharmaceutical Economics
摘 要:目的探讨在小儿支气管哮喘慢性持续期的治疗中应用药物雾化联合小儿推拿疗法的临床效果。方法选取2019年1月至2021年1月沈阳市儿童医院收治的88例小儿支气管哮喘慢性持续期患儿作为研究对象,按随机数字表法分为对照组与观察组,各44例。对照组患儿单纯接受药物雾化治疗,观察组患儿在对照组基础上接受小儿推拿疗法(主要采用海派儿科推拿手法)治疗,比较两组治疗有效率、炎症介质和肺功能。结果观察组治疗有效率为97.72%,高于对照组的84.09%,差异有统计学意义(P<0.05);治疗前,两组炎症介质、肺功能比较,差异无统计学意义(P>0.05);治疗后,观察组肿瘤坏死因子-α(TNF-α)、免疫球蛋白E(IgE)、白细胞介素-4(IL-4)水平低于对照组,观察组患儿治疗后用力肺活量(FVC)、第一秒钟用力呼气容积(FEV_(1))、呼气峰流速(PEF)水平高于对照组,差异有统计学意义(P<0.05)。结论药物雾化联合小儿推拿疗法治疗小儿支气管哮喘慢性持续期效果较好。Objective To explore the therapeutic effect of the application of drug atomization combined with pediatric massage therapy in the treatment of chronic persistent period of bronchial asthma in children.Methods A totall of 88 child patients with chronic persistent bronchial asthma admitted in Shenyang Children's Hospital from January 2019 to January 2021 were selected as the observation objects.According to the random number table method,they were divided into a control group and an observation group,with 44 cases in each group.The children in the control group received only drug atomization treatment,while the children in the observation group received pediatric massage therapy(mainly using Shanghai-style pediatric massage manipulation)plus drug atomization treatment.The therapeutic efficiency,inflammatory mediators and lung function were compared between the 2 groups.Results The effective rate of treatment in the observation group was 97.72%,which was higher than 84.09%in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in inflammatory mediators and lung function between the 2 groups(P>0.05);after treatment,the levels of tumor necrosis factor-α(TNF-α),immunoglobulin E(IgE)and interleukin-4(IL-4)in the observation group were lower than those in the control group,and the forced vital capacity of the children in the observation group after treatment(FVC),forced expiratory volume in one second(FEV_(1)),peak expiratory flow(PEF)levels were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Drug nebulization combined with pediatric massage therapy is effective in the treatment of children with chronic persistent bronchial asthma.
分 类 号:R541.4[医药卫生—心血管疾病] R972[医药卫生—内科学]
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