基于数据挖掘方法探讨名老中医治疗眩晕用药规律  

Discussion on Medication Rules in Treatment of Vertigo by Famous TCM Physician Based on Data Mining

作　　者：高贤波[1] 张砚[1] 王东军 宋思敏 王益民[1] GAO Xianbo;ZHANG Yan;WANG Dongjun;SONG Simin;WANG Yimin(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学,天津301617

出　　处：《辽宁中医药大学学报》2022年第3期64-68,共5页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金(81303144)。

摘　　要：目的探讨张伯礼教授治疗眩晕的用药规律。方法筛选张伯礼教授2012年1月—2017年12月治疗眩晕的门诊处方590首,对其进行频数分析、关联规则分析和聚类分析。结果张教授治疗眩晕的常用中药有48味,用药频率大于50%的有6味中药,分别为丹参、郁金、葛根、夏枯草、天麻和杜仲。所使用药物药性以寒性为主;药味以苦、甘、辛为主;归经以肝经、心经、肺经居多,尤其以肝经药物突出。关联规则得出药对27对,两味药关联规则17条,三味药关联规则17条。聚类分析得到5类,C1:川芎、白芷、天麻、菊花、珍珠母、夏枯草、黄芩;C2:杜仲、桑枝、葛根、当归、牛膝、牡蛎;C3:丹参、郁金;C4:黄连、半夏、茯苓;C5:麦冬、知母、首乌藤。结论通过数据分析得出张伯礼教授治疗眩晕时主要以活血化瘀、祛风通络、平抑肝阳、清热泻火、滋补肝肾、养阴安神为治则进行辨证论治。Objective To analyze the medication rule of professor ZHANG Boli in the treatment of vertigo.Methods The 590 outpatient prescriptions for the treatment of vertigo by professor ZHANG Boli from January 2012 to December 2017 were screened,and frequency analysis,association rule analysis and cluster analysis were performed on them.Results There were 48 kinds of drugs commonly used by professor ZHANG for the treatment of vertigo,and 6 kinds of drugs with a frequency of more than 50%were Danshen(Salviae Miltiorrhizae Radix Et Rhizoma),Yujin(Curcumae Radix),Gegen(Puerariae Lobatae Radix),Xiakucao(Prunellae Spica),Tianma(Gastrodiae Rhizoma)and Duzhong(Eucommiae Cortex).The medicinal properties were mainly cold;the medicinal taste was mainly bitter,sweet and pungent;the main meridians were the liver meridian,the heart meridian,and the lung meridian,especially the liver meridian.The association rules yielded 27 pairs of drugs and 17 association rules for two kinds of drugs,17 association rules for three kinds of drugs.Cluster analysis yielded 5 categories,C1:Chuanxiong(Rhizoma),Baizhi(Angelicae Dahuricae Radix),Tianma(Gastrodiae Rhizoma),Juhua(Chrysanthemi Flos),Zhenzhumu(Margaritifera Concha),Xiakucao(Prunellae Spica),Huangqin(Scutellariae Radix);C2:Duzhong(Eucommiae Cortex),Sangzhi(Mori Ramulus),Gegen(Puerariae Lobatae Radix),Danggui(Angelicae Sinensis Radix),Niuxi(Achyranthis Bidentatae Radix),Muli(Ostreae Concha);C3:Danshen(Salviae Miltiorrhizae Radix Et Rhizoma),Yujin(Curcumae Radix);C4:Huanglian(Coptidis Rhizoma),Banxia(Pinelliae Rhizoma),Fuling(Poria);C5:Maidong(Ophiopogonis Radix),Zhimu(Anemarrhenae Rhizoma),Shouwuteng(Polygoni Multiflori Caulis).Conclusion Through data analysis,it was concluded that professor ZHANG Boli’s treatment of vertigo was mainly based on promoting blood circulation and removing blood stasis,dispelling wind and dredging collaterals,suppressing liver-Yang,clearing heat and reducing fire,nourishing liver and kidney,nourishing Yin and calming nerves as the treatment principles.

关 键 词：数据挖掘 关联规则 聚类分析 眩晕 用药规律 

分 类 号：R255.3[医药卫生—中医内科学]