陈锐从“毒”论治糖尿病肾病经验  

Professor Chen Rui’s experience in treating diabetic nephropathy based on the syndrome differentiation of toxins

作　　者：周兴庆 陈锐[1] ZHOU Xingqing;CHEN Rui(School of Basic Medical Science,Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]长春中医药大学基础医学院,长春130117

出　　处：《吉林中医药》2022年第5期542-545,共4页Jilin Journal of Chinese Medicine

基　　金：吉林省教育厅科技项目(JJKH20200883KJ);长春中医药大学科研发展基金项目(0152019PY015)。

摘　　要：“毒”由正虚、邪盛难解而成,伏藏体内而不觉,伺机而发病且多变,严重影响糖尿病肾病的发生发展进程。糖尿病肾病证属本虚标实,其标之痰瘀互结可阻碍气血生化运行,因而毒邪不解、诸药不运则难获良效,故治疗当先解毒通络。基于“毒损肾络”思想及“态靶”辨证理论,陈锐教授注重糖尿病肾病之“态”,针对痰毒、瘀毒、糖毒、脂毒、本虚等数个靶点,有机组合多个小靶方,创立“态方”——消肾方,攻补兼施,标本同治。Toxins,which are caused by the deficient vital qi and exuberant pathogens,hidden in the body unknowingly,ready to induce diseases and changeable,substantially affect the occurrence and development of diabetic nephropathy.Diabetic nephropathy is known to be characterized by a syndrome of deficiency in its root cause and excess in its manifestations,in which the intermingling of phlegm and blood stasis can hinder the generation,transformation,transportation and operation of qi and blood.Therefore,its treatment should place a priority on eliminating toxins and dredging collaterals.Based on the thought of“toxins impairing kidney collaterals”and the theory of state-target syndrome differentiation,Professor Chen Rui pays attention to the states of the disease,and directs her treatment at several targets such as phlegm,blood stasis,hyperglycemia,hyperlipidemia and deficiency of the body,etc.She combines several small target prescriptions to create the Xiaoshen Fang for the state treatment of the disease.The prescription combines the purgation method with the tonifying method,deals with its manifestations and root cause simultaneously,in a bid to achieve a remarkable clinical effect.

关 键 词：糖尿病肾病 毒损肾络 “态靶”辨证 消肾方 

分 类 号：R587.2[医药卫生—内分泌]