D-Dimer检测在诊断口腔疾病中的应用  

Application of D-Dimer Detection in the Diagnosis of Oral Diseases

作　　者：于洋[1] 魏清[1] YU Yang;WEI Qing(Department of Laboratory Medicine,Stomatological Hospital,Jilin University,Changchun,Jilin Province,130021 China)

机构地区：[1]吉林大学口腔医院检验科,吉林长春130021

出　　处：《系统医学》2022年第4期195-198,共4页Systems Medicine

摘　　要：D-二聚体(D-Dimer)是来源于纤维蛋白单体经过FXIII交联后,再经纤溶酶水解作用所产生的一种特异性的降解产物,可以直接反映在人体内凝血功能和纤溶活性酶的状态。近年来,临床上常用D-Dimer来监测凝血功能障碍性疾病和血栓性疾病。但是随着近些年更加深入的研究发现,D-Dimer在恶性肿瘤、肝脏疾病、肺栓塞、妊高症孕妇、脑梗死、系统性红斑狼疮等疾病中也有明显的改变,联合其他检查可提高疾病诊断的特异性与灵敏度。D-dimer(D-Dimer)is a specific degradation product derived from fibrin monomers cross-linked by FXIII and then hydrolyzed by plasmin.It can directly reflect the state of coagulation function and fibrinolytic activity in the human body.In recent years,D-Dimer is commonly used clinically to monitor coagulation disorders and thrombotic diseases.However,with more in-depth research in recent years,it has been found that D-Dimer also has obvious changes in malignant tumors,liver diseases,pulmonary embolism,pregnancy-induced hypertension,cerebral infarction,systemic lupus erythematosus and other diseases.Combining other tests can improve the specificity and sensitivity of disease diagnosis.

关 键 词：D-二聚体 颌面部间隙感染 口腔颌面部恶性肿瘤 下肢深静脉血栓 

分 类 号：R4[医药卫生—临床医学]