急性大失血患者输血治疗方法及其临床效果分析  

Analysis of the Treatment Methods and Clinical Effects of Blood Transfusion in Patients with Acute Massive Blood Loss

作　　者：陈清庭 蒋俊煌[1] 蒋剑洪 张祖程 詹芳芳 CHEN Qingting;JIANG Junhuang;JIANG Jianhong;ZHANG Zucheng;ZHAN Fangfang(Department of Blood Transfusion,Affiliated Hospital of Putian University,Putian,Fujian Province,351100 China)

机构地区：[1]莆田学院附属医院输血科,福建莆田351100

出　　处：《中外医疗》2022年第4期70-73,共4页China & Foreign Medical Treatment

摘　　要：目的对输血治疗在急性大失血患者疾病治疗中的临床运用效果进行观察。方法方便选取该院2018年1月—2020年12月收治的急性大失血患者270例作为研究对象,按随机数字表法将270例患者分成甲组、乙组、丙组,甲组(130例)采取红细胞和血浆输注治疗,乙组(131例)采取红细胞、血浆及冷沉淀输注治疗,丙组(9例)采取红细胞加血浆、冷沉淀及血小板输注治疗。对以上3组患者的治疗效果及凝血功能变化情况进行观察与比较。结果丙组治疗后总有效率(100.00%)高于甲组(69.23%)、乙组(77.10%),差异有统计学意义(χ^(2)=2.532、5.624,P<0.05);丙组患者平均止血时间及24 h悬浮红细胞持续用量均优于甲组及乙组患者,差异有统计学意义(P<0.05);3组患者治疗后的FIB、TT、PT、APTT等指标均优于治疗前,差异有统计学意义(P<0.05);丙组患者治疗后的FIB、TT、PT、APTT等指标均优于甲组治疗后、乙组治疗后,差异有统计学意义(P<0.05)。结论对急性大失血患者采取红细胞加血浆、冷沉淀及血小板联合输注治疗,效果甚佳,能在一定程度改善患者的凝血功能,具备临床推广价值。Objective To observe the clinical application effect of blood transfusion therapy in the treatment of patients with acute massive blood loss.Methods 270 patients with acute massive blood loss treated in the hospital from January 2018 to December 2020 were conveniently selected as the research objects.According to the random number table method,270 patients were divided into group A,group B and group C.Group A(130 cases)was treated with red blood cell and plasma infusion,group B(131 cases)was treated with red blood cell,plasma and cryoprecipitate infusion,and group C(9 cases)was treated with red blood cell plus plasma,cryoprecipitate and platelet infusion.Observed and compared the treatment effect and coagulation function changes of the above three groups of patients.Results The total effective rate(100.00%)in group C after treatment was higher than that in group A(69.23%)and group B(77.10%),the difference was statistically significant(χ^(2)=2.532,5.624,P<0.05).The average hemostasis time and 24 h continuous dosage of suspended red blood cells in group C patients were better than those in group A and group B,the difference was statistically significant(P<0.05).The FIB,TT,PT,APTT and other indicators of the three groups of patients after treatment were better than those of this group before treatment,the difference was statistically significant(P<0.05).The FIB,TT,PT,APTT and other indicators of patients in group C after treatment were better than those in group A and group B after treatment,the difference was statistically significant(P<0.05).Conclusion The combined treatment of red blood cell plus plasma,cryoprecipitate and platelet transfusion is very effective for patients with acute massive blood loss.It can improve the coagulation function of patients to a certain extent and has clinical promotion value.

关 键 词：急性大失血 输血治疗 血小板 冷沉淀凝血因子 

分 类 号：R5[医药卫生—内科学]