人工流产术后应用短效口服避孕药与雌孕激素序贯疗效对比  

Comparison of curative effect of short-acting oral contraceptives and estrogen-progesterone sequential therapy for treating women after abortion

作　　者：李娜[1] 李宝鑫 韩晓佳 LI Na;LI Baoxin;HAN Xiaojia(Jingnan Medical Branch,PLA General Hospital,Beijing,100071;731 Hospital of China Aerospace Science and Industry Corporation)

机构地区：[1]解放军总医院京南医疗区,北京100071 [2]中国航天科工集团七三一医院

出　　处：《中国计划生育学杂志》2022年第5期1026-1030,共5页Chinese Journal of Family Planning

摘　　要：目的:比较短效口服避孕药与雌孕激素序贯应用于人工流产术后恢复疗效.方法:2020年1月—2020年9月在本院门诊行人工流产术女性120例,按术后治疗方式不同分为对照组、观察1组和观察2组各40例,对照组给予常规消炎治疗,观察1组在对照组基础上给予口服短效避孕药治疗,观察2组在对照组基础上给予口服雌孕激素序贯治疗.对比术后恢复情况、性激素水平及并发症.结果:治疗后,与对照组相比,观察1组和观察2组阴道出血持续时间和月经复潮时间、出血量均减少,观察1组阴道持续出血时间、出血量少于观察2组(均P<0.05);子宫内膜厚度观察1组小于观察2组但均较治疗前增加且大于对照组,月经不适量表(MDQ)评分观察1组和观察2组均低于对照组(均P<0.05);促卵泡生成素、促黄体生成素、雌二醇水平观察1组和观察2组无差异但均高于对照组(P<0.05),并发症发生率观察1组和观察2组无差异(7.5%比5.0%)但均低于对照组(32.5%)(P<0.05).结论:人工流产术后采用口服短效避孕药或雌孕激素序贯治疗均可减少受术者术后出血量,促进月经周期恢复,改善月经不适症状,提高性激素水平,减少术后并发症发生.Objective: To compare the curative effect of short-acting oral contraceptives and estrogen-progesterone sequential therapy for treating women after abortion. Methods: 120 women who underwent abortion were included and were divided into three groups(40 cases in each group) according to the different postoperative treatments between January 2020 and September 2020. The women in the control group were given conventional treatment, and the women in group A were given short-acting oral contraceptives combined with conventional treatment, and the women in group B were given oral estrogen-progesterone sequential therapy combined with conventional treatment. The postoperative recovery status, the sex hormones levels, and the incidence of postoperative complications of the women were compared among the three groups. Results: After treatment, the duration of vaginal bleeding, the menstrual recovery time, and the bleeding volume of the women in group A and in group B were significantly less than those of the women in the control group, and the duration of vaginal bleeding and the bleeding volume of the women in group A were significantly less than those of the women in group B(all P<0.05). The endometrial thickness of the women in group A was significantly thinner than that of the women in group B, and which of the women in both group B and group A after treatment was significantly thicker than that before treatment, and which of the women in both group B and group A was significantly thicker than that of the women in the control group. The score of menstrual discomfort scale(MDQ) of the women in both group B and group A was significantly was significantly lower than that of the women in the control group(all P<0.05).The levels of follicle-stimulating hormone(FSH),luteinizing hormone,and estradiol of the women had no significant difference between group A and group B,but which of the women in both group B and group A was significantly higher than that of the women in the control group(P<0.05).The incidence of complications(

关 键 词：人工流产 短效口服避孕药 雌孕激素序贯 术后月经恢复 性激素 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]