改良腹腔镜手术治疗卵巢子宫内膜异位囊肿伴不孕症疗效及对T淋巴细胞及妊娠结局影响  

Efficacy of modified laparoscopic surgery for treating infertility patients with ovarian endometriosis cyst and its influence on their T-lymphocytes level and pregnancy outcomes

作　　者：马燕玲[1] 古丽加耐提·艾耐托拉 MA Yanling;GU LI JIA NAI TI.Ai nai tuo la(The First Affiliated Hospital of Xinjiang Medical University,Wulumuqi,Xinjiang,830054)

机构地区：[1]新疆医科大学第一附属医院,乌鲁木齐830054

出　　处：《中国计划生育学杂志》2022年第5期1036-1039,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨改良腹腔镜手术治疗卵巢子宫内膜异位囊肿伴不孕症疗效及对T淋巴细胞及妊娠结局影响.方法:收集本院收治的123例卵巢子宫内膜异位囊肿伴不孕症患者,根据治疗方式分组,本别采用改良腹腔镜下卵巢囊肿剥除术治疗(改良组60例)或常规腹腔镜下卵巢囊肿剥除术治疗(常规组63例),比较临床疗效.结果:改良组术后首次肛门排气时间(1.3±0.4d)、术中出血量(23.2±3.9ml)及住院时间(6.5±1.1d)均低于对照组(1.9±0.6d、29.5±4.5 ml、8.3±1.4d),术后卵巢储备功能相关性激素指标改善程度均优于常规组,T淋巴细胞亚群细胞指标优于常规组,妊娠率(67.5%)高于常规组(44.4%)(均P<0.05).结论:子宫内膜异位症伴不孕症采用改良腹腔镜手术提高了治疗效果,减小了对卵巢功能及免疫功能影响,更利于术后患者康复,提高妊娠率.Objective: To investigate the efficacy of modified laparoscopic surgery for treating infertility patients with ovarian endometriosis cyst, and to study its influence on their T-lymphocytes level and pregnancy outcomes. Methods: 123 infertility patients with ovarian endometriosis cysts were selected and were divided into two groups according to the different treatments. 60 patients in the study group were treated by modified laparoscopic oophorocystectomy, while 63 patients in the control group were treated by conventional laparoscopic oophorocystectomy. The clinical efficacy of the patients was compared between the two groups. Results: The time of the first postoperative anal exhaust(1.3±0.4 d), the intraoperative blood loss(23.2±3.9 ml), and the hospital stay(6.5±1.1 d) of the patients in the study group were significantly lower than those(1.9±0.6 d, 29.5±4.5 ml, and 8.3±1.4 d) of the patients in the control group. The improvement degrees of the sex hormone indexes related to ovarian reserve function, and the levels of T lymphocyte subgroup indexes of the patients in the study group after operation were significantly better than those of the patients in the control group. The pregnancy rate(67.5%) of the patients in the study group was significantly higher than that(44.4%) of the patients in the control group(all P<0.05). Conclusion: Modified laparoscopic surgery for treating infertility patients with ovarian endometriosis cyst can increase the effectiveness, and reduce the adverse effect on their ovarian reserve function and immune function, which is beneficial to their rehabilitation after operation and improve their pregnancy rate.

关 键 词：子宫内膜异位囊肿伴不孕症 改良腹腔镜手术 手术指标 卵巢储备功能 免疫功能 妊娠率 

分 类 号：R713.6[医药卫生—妇产科学]