经尿道摩西钬激光前列腺剜除术与经尿道双极等离子前列腺剜除术治疗良性前列腺增生的疗效及安全性比较  

Comparative study between transurethral holmiun laser enucleation of the prostate and transurethral bipolar plasmakinetic enucleation and resection of the prostate for benign prostatic hyperplasia

作　　者：孙允冀 刘荷臣 程琳[1] 于广洋 魏强[1] 魏巍[1] Sun Yunji;Liu Hechen;Chen Lin;Yu Guangyang;Wei Qiang;Wei Wei(Department of Urology,Shandong Provincial Third Hospital Affiliated to Shandong University,Jinan 250000,China)

机构地区：[1]山东大学附属山东省立第三医院泌尿外科,山东省结石病防治中心,济南250000

出　　处：《国际泌尿系统杂志》2022年第3期478-481,共4页International Journal of Urology and Nephrology

摘　　要：目的探讨经尿道摩西钬激光前列腺剜除术(HoLEP)与经尿道双极等离子前列腺剜除术(PKERP)治疗良性前列腺增生的疗效差异。方法选取2018年1月至2019年12月山东大学附属省立第三医院泌尿外科收治的49例良性前列腺增生患者,其中23例采用120 W摩西钬激光行HoLEP治疗(HoLEP组),26例行PKERP治疗(PKERP组),术后随访3个月,比较两组患者的手术时间、术中出血量、前列腺切除体积、术后并发症发生率以及术后3个月患者的最大残余尿量、国际前列腺症状评分(IPSS)、生活质量(QOL)评分及最大尿流率(Q_(max))情况。结果HoLEP组患者的手术时间、术中出血量均低于PKERP组(均P<0.05);HoLEP组的切除前列腺组织较PKERP组更多(P=0.043)、术后尿管留置时间更短(P=0.001);两组术后总体并发症发生率比较,差异无统计学意义(4.35%vs.7.69%,P>0.05);两组患者术后3个月的膀胱残余尿量、IPSS、QOL评分、最大尿流率与术前比较均有显著改善(均P<0.05),但两组间比较,差异均无统计学意义(均P>0.05)。结论HoLEP与PKERP治疗良性前列腺增生均可以取得良好的治疗效果,且HoLEP在手术时间、术中出血量、前列腺切除重量、术后恢复方面均优于PKERP。Objective To compare the efficacy and safety between holmiun laser enucleation of the prostate(HoLEP)and transurethral bipolar plasmakinetic enucleation and resection of the prostate(PKERP)for the treatment of benign prostatic hyperplasia(BPH).Methods A total of 49 patients with BPH admitted to the department of urology,the third affiliated hospital of Shandong university from January 2018 to December 2019 were selected.Among them,23 patients were treated with HoLEP(HoLEP group)and 26 patients were treated with PKERP(PKERP group).The postoperative follow-up was three months,and the operative time,intraoperative blood loss,prostatectomy volume,postoperative complication rate,maximum residual urine volume,international score of prostate symptoms(IPSS),quality of life(QOL)score and maximum urine flow rate(Q_(max))were compared between the two groups three months after surgery.Results The operative time and intraoperative blood loss in HoLEP group were lower than those in PKERP group(all P<0.05).More prostate tissue was removed in HoLEP group than in PKERP group(P=0.043),and the duration of catheter indwelling after operation(P=0.001).There was no significant difference in the incidence of overall postoperative complications between the two groups(4.35%vs.7.69%,P>0.05).Bladder residual urine volume,IPSS,QOL score and maximum urine flow rate in two groups were significantly improved three months after surgery compared with that before surgery(all P<0.05),but there was no statistical significance between two groups(all P>0.05).Conclusions Both HoLEP and PKERP in the treatment of BPH can achieve good therapeutic effect,and HoLEP is superior to PKERP in terms of operative time,intraoperative blood loss,weight of prostate resection and postoperative recovery.

关 键 词：前列腺增生 经尿道前列腺切除术 钬 经尿道等离子双极电切术 

分 类 号：R699.8[医药卫生—泌尿科学]