声表面波微流控液滴生成技术研究进展  

Development of Surface Acoustic Wave Microfluidic Droplet Generation Technology

作　　者：杨紫薇 李磊 杨磊 金少搏 张传禹 韦学勇[1] YANG Zi-wei;LI Lei;YANG Lei;JIN Shao-bo;ZHANG Chuan-yu;WEI Xue-yong(State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi 710049;Xi'an Jiaotong University Suzhou Institute, Suzhou, Jiangsu 215123;Henan Key Laboratory of Intelligent Manufacturing Mechanical Equipment, Zhengzhou University of Light Industry, Zhengzhou, Henan 450002)

机构地区：[1]西安交通大学机械制造系统工程国家重点实验室,陕西西安710049 [2]西安交通大学苏州研究院,江苏苏州215123 [3]郑州轻工业大学河南省机械装备智能制造重点实验室,河南郑州450002

出　　处：《液压与气动》2022年第5期118-125,共8页Chinese Hydraulics & Pneumatics

基　　金：国家自然科学基金(52075432,51905413);国家重点研发计划(2020YFB2009002);江苏省自然科学基金(BK20180239)。

摘　　要：微液滴是一种十分优秀的微反应器,在化学合成、生物检测及细胞研究等领域应用广泛。近年来,声表面波微流控技术发展迅速,在微液滴制备中具有重要应用前景。首先简单回顾了微液滴和声表面波微流控的研究发展历程,然后重点介绍了声表面波微流控液滴生成的工作原理、器件结构、液滴生成过程及工艺参数等;同时介绍了声表面波微流控核壳微液滴的可控生成机理及其制造过程。最后总结并展望了该技术在生化检测、生物3D打印等领域的应用前景。Microdroplet is a very important micro reactor,which can be widely used in chemical synthesis,bio detection and cell research.In recent years,surface acoustic wave(SAW)microfluidic technology develops rapidly,and has the promising application for microdroplet generation.This paper first simply introduces the research and development history of microdroplet and SAW microfluidic;then mainly demonstrates the working mechanism,device structure,fabrication process and parameters of the microdroplet fabrication with the help of SAW microfluidic.Meanwhile,the controllable mechanism and fabrication process of the core shell droplet are discussed.Finally,the application potential for biochemical detection and 3D bio printing is concluded and prospected.

关 键 词：微流控 声表面波 液滴生成 核壳液滴 

分 类 号：TH137[机械工程—机械制造及自动化]