不同抗生素对子宫下段剖宫产术后感染率的影响  

Influence of Different Antibiotics on Infection Rate After Low Uterine Cesarean Section

作　　者：王雪莹 范雪 艾浩 Wang Xue-ying;Fan Xue;Ai Hao(Shenyang Women's and Children's Hospital,Shenyang 110011,Liaoning Province,China;Third Affiliated Hospital of Jinzhou Medical University,Jinzhou 121000,Liaoning Province,China)

机构地区：[1]沈阳市妇婴医院,辽宁沈阳110011 [2]锦州医科大学附属第三医院,辽宁锦州121000

出　　处：《中国社区医师》2022年第12期44-46,共3页Chinese Community Doctors

摘　　要：目的:探讨子宫下段剖宫产术后应用不同种类抗生素的临床价值。方法:随机选取2014年1月-2020年7月于沈阳市妇婴医院行择期子宫下段剖宫产的足月妊娠妇女89例。按照用药方式将患者分为4组,第1组(22例)患者采用五水头孢;第2组患者(22例)应用氨曲南;第3组(22例)患者用药为克林霉素联合氨曲南;第4组患者(23例)为无抗生素组,单纯以甲硝唑冲洗腹腔。回顾性分析子宫下段剖宫产产妇术后应用抗生素情况,使用不同种类抗生素的临床效果。结果:术后疗效、术后中性粒细胞异常率、术后感染率比较,4组之间的差异无统计学意义(P>0.05)。结论:对于没有基础性疾病的妊娠期妇女,子宫下段剖宫产术后应用五水头孢、氨曲南、克林霉素配伍氨曲南这三种抗生素应用方案没有区别。同时,对于关腹前以甲硝唑冲腹腔,术后不使用大剂量抗生素静脉滴注也可以达到同样的效果。Objective:To investigate the clinical value of different antibiotics after lower uterine cesarean section.Methods:A total of 89 full-term pregnant women who underwent elective lower uterine cesarean section in Shenyang Women's and Children's Hospital from January 2014 to July 2020 were randomly selected.The patients were divided into 4 groups according to the medication method.Group 1(22 cases)received cephalosporin pentahydrate;Group 2(22 cases)received aztreonam;Group 3(22 cases)received clindamycin combined with aztreonam;Group 4(23 cases)received no antibiotics and the abdominal cavity was washed with metronidazole.The application of antibiotics after lower uterine cesarean section and the clinical effects of different types of antibiotics were retrospectively analyzed.Results:There was no statistically significant difference in postoperative curative effect and intraoperative neutrophil abnormality rate between the four groups(P>0.05).Conclusion:For pregnant women without underlying diseases,there is no difference in the application of three antibiotics regimens of ceftriaxone pentahydrate,aztreonam,and clindamycin with aztreonam after lower uterine cesarean section.At the same time,the same effect can be achieved by flushing the abdominal cavity with metronidazole before abdominal closure and no intravenous drip of high-dose antibiotics after operation.

关 键 词：剖宫产 抗生素 五水头孢 氨曲南 克林霉素 

分 类 号：R719.8[医药卫生—妇产科学]