黏液嵌塞致急性肺不张1例并文献分析  

Acute atelectasis with mucus embolism:a case report and literature review

作　　者：宋建奇 房颖 卜小宁[2] 姜纯国[2] 冯晓凯 孙海燕 SONG Jianqi;FANG Ying;BU Xiaoning

机构地区：[1]北京市大兴区中西医结合医院呼吸科,北京100076 [2]首都医科大学附属北京朝阳医院呼吸与危重症医学科

出　　处：《临床急诊杂志》2022年第4期289-293,共5页Journal of Clinical Emergency

基　　金：首都卫生发展科研专项(No:2018-2-1062)。

摘　　要：气道黏膜被覆一层黏液物质,正常气道黏液由97%的水和3%的固体(黏蛋白、非黏蛋白、盐类、脂类和细胞碎片)组成,浓度与蛋清相似[1]。气道分泌的黏液具有保护气道、湿润空气等作用,气道黏液被覆在气道纤毛之上,可黏附吸入的颗粒物、气体和病原体等有害物质,通过纤毛摆动或者咳嗽反射将其转运出体外,是呼吸道重要的防御机制[2]。如果黏蛋白过度分泌或黏液表面液体丢失,则黏液固体成分增加,导致黏弹性增加,更容易黏附在气道壁上,而不易被清除[3]。We retrospectively analyzed the clinical materials,diagnosis and treatment of a case of acute atelectasis caused by mucus impaction in Beijing Chaoyang Hospital.We logged on the database of Wanfang,Weipu and China HowNet by using "mucus embolism or mucus impaction" and "atelectasis" as Chinese search terms,and logged on the Pubmed database by using "atelectasis or lung collapse" and "mucous plug" or "mucoid impaction" as English search terms.The database were retrieved until November 2018,and medical records were summarized and analyzed.The causes of mucus impaction atelectasis are various,and the courses of the disease are different.Clinically,if the respiratory symptoms of patients do not alleviate after routine treatment or unexplainable dyspnea occurs quickly,we should consider the possibility of mucus impaction atelectasis.The progress of the disease can be blocked by timely intervention with bronchoscope for further treatment time.

关 键 词：黏液栓 黏液嵌塞 肺不张 

分 类 号：R563.4[医药卫生—呼吸系统]