3.0T磁共振DWI图纹理分析在预测局部进展期直肠癌新辅助放化疗抗拒的应用价值  

The value of 3.0T magnetic resonance-DWI image texture analysis in predicting resistance to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

作　　者：杨志宏[1] 曹杰[1] 刘慧 张佳[1] 朱少群[1] 吕敦召 是德海[1] YANG Zhihong;CAO Jie;LIU Hui;ZHANG Jia;ZHU Shaoqun;LYU Dunzhao;SHI Dehai(Imaging Center,Jiujiang NO.1 People′s Hospital in Jiangxi Province,Jiujiang 332000,China;Department of Imaging,Jiujiang University Duchang Hospital in Jiangxi Province,Jiujiang 332600,China)

机构地区：[1]江西省九江市第一人民医院影像中心,江西九江332000 [2]江西省都昌县人民医院影像科,江西九江332600

出　　处：《中国现代医生》2022年第13期126-128,133,共4页China Modern Doctor

基　　金：江西省卫健委科技计划项目(202140241)。

摘　　要：目的探讨新辅助放化疗治疗局部进展期直肠癌抗拒预测中3.0T磁共振DWI图纹理分析的应用价值。方法回顾性选取2018年2月至2020年6月于江西省九江市第一人民医院行MR检查的直肠癌患者40例,依据新辅助放化疗效果分为抗拒组(n=20)、有效组(n=20),均接受根治手术前新辅助放化疗、3.0T磁共振检查及DWI图纹理分析,然后统计分析两组患者的3.0T磁共振DWI图纹理分析参数比较。结果抗拒组患者的能量平均、能量方差、直方图能量、相关度平均、SdGa 04、SdGa 11、SdGa 47均高于有效组,差异有统计学意义(P<0.05);高强度小区域强调、逆方差平均、shade聚类方差、Gabor 11、Cabor 26、Cabor 47、SdGa 00、SdGa 37、SdGa 43、SdGa 44均低于有效组,差异有统计学意义(P<0.05)。结论局部进展期直肠癌新辅助放化疗抗拒预测中3.0T磁共振DWI图纹理分析的应用价值高。Objective To explore the application value of image texture analysis of 3.0T magnetic resonance(MR)diffusion-weighted imaging(DWI)in predicting resistance to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.Methods A total of 40 patients with rectal cancer undergoing MR examination in Jiujiang NO.1 People′s Hospital from February 2018 to June 2020 were retrospectively selected and divided into the resistant group(n=20)and the effective group(n=20)based on the efficacy of neoadjuvant chemoradiotherapy.All patients received neoadjuvant chemoradiotherapy,3.0T MRI examination and DWI image texture analysis before radical surgery,and then the parameters for 3.0T MRI-DWI image texture analysis were statistically analyzed and compared between the two groups.Results The mean energy,energy variance,histogram energy,mean correlation,SdGa 04,SdGa 11,and SdGa 47 of patients in the resistant group were higher than those in the effective group,with statistically significant difference(P<0.05).And the high-intensity small region emphasis level,mean inverse variance,shade clustering variance,Gabor 11,Cabor 26,and Cabor 47,SdGa 00,SdGa 37,SdGa 43 and SdGa 44 were lower than those in the effective group,with statistically significant difference(P<0.05).Conclusion 3.0T MRI-DWI image texture analysis is of high value in predicting resistance to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

关 键 词：新辅助放化疗 局部进展期直肠癌 抗拒 有效 3.0T磁共振 DWI图纹理分析 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.37[医药卫生—诊断学]