N-(9H-芴-9-甲氧羰基氧)丁二酰亚胺合成研究  

Study on the Synthesis of N-(9H-Fluoren-9-ylmethoxycarbonyloxy) Succinimide

作　　者：张广平 臧阳陵 周锦萍 李萍 陈明 王燕 黄炜 罗先福 ZHANG Guang-ping;ZANG Yang-ling;ZHOU Jin-ping;LI Ping;CHEN Ming;WANG Yan;HUANG Wei;LUO Xian-fu(Hunan Haili Changde Pesticide&Chemical Industry Co.,Ltd.,Changde 415001,China;Hunan Research Institute of Chemical Industry Co.,Ltd.,National Engineering Research Center for Agrochemicals,Changsha 410014,China;Hunan Province Key Laboratory for Agrochemicals,Changsha 410014,China)

机构地区：[1]湖南海利常德农药化工有限公司,湖南常德415001 [2]湖南化工研究院有限公司国家农药创制工程技术研究中心,湖南长沙410014 [3]农用化学品湖南省重点实验室,湖南长沙410014

出　　处：《精细化工中间体》2022年第1期24-27,共4页Fine Chemical Intermediates

基　　金：湖湘青年英才项目(2019RS2060)。

摘　　要：9-芴甲醇与光气反应合成9-芴甲酯(FMOC-Cl),不经分离直接与N-羟基丁二酰亚胺反应,一锅法合成N-(9H-芴-9-甲氧羰基氧)丁二酰亚胺(FMOC-OSu),总收率95%,产品纯度98%。N-(9 H-Fluoren-2-ylmethoxycarbonyloxy) succinimide was synthesized through a reaction between Nhydroxysuccinimide and 1-(9-fluorenyl)methylchloroformate which was obtained from a reaction between 9 HFluorene-9-methanol and phosgene without separation.The yield of this one-pot process was of 95% with a purity of 98%.

关 键 词：N-(9H-芴-9-甲氧羰基氧)丁二酰亚胺 光气 合成 

分 类 号：TQ203[化学工程—有机化工]