磺胺二甲嘧啶与地克珠利治疗塞北兔球虫病的效果比较研究  

Comparison of Sulfamadiazine and Dixide in the Treatment of Coccidiosis in Saibei Rabbits

作　　者：关琛 逯春香 吕江 李新华 阮慧杰 崔平 方素芳[4] GUAN Chen;LU Chunxiang;YU Jiang;LI Xinhua;RUAN Huijie;CUI Ping;FANG Sufang(Hebei Province Zhangjiakou City Animal Husbandry Technology Extension Station,Zhangjiakou 075000;Zhangjiakou Gity Animal Health Supervision Institute,Hebei Province,Zhangjiakou 075000;Qiaodong District Bureau of Agriculure and Rural Affairs,Zhangjiakou City,Hebei Province,Zhangjiakou 075000;School of Animal Science and Technology,Hebei North University,Zhangjiakou 075000)

机构地区：[1]河北省张家口市畜牧技术推广站,张家口075000 [2]河北省张家口市动物卫生监督所,张家口075000 [3]河北省张家口市桥东区农业农村局,张家口075000 [4]河北北方学院动物科技学院,张家口075000

出　　处：《中国养兔》2022年第2期11-14,共4页Chinese Journal of Rabbit Farming

基　　金：河北省自然科学基金和重点基础研究专项(C2019405052)。

摘　　要：为探讨磺胺二甲嘧啶与地克珠利对塞北兔自然感染球虫病的治疗效果。试验选取日龄、营养状况、发病程度一致、体重差异性不显著的30只塞北兔为试验动物,将其随机分成3组,A组(磺胺二甲嘧啶组)、B组(地克珠利组)、C组(空白对照组),每组10只。向A组饮水中添加500 mg/kg磺胺二甲嘧啶,向B组饲料中添加2 mg/kg地克珠利,连续给药7 d,然后饲喂常规饲料直至试验结束。C组作为对照组正常饮水,喂常规饲料。以用药后平均增重、平均排卵量、存活率作为判定药物治疗疗效的主要依据。结果表明:磺胺二甲嘧啶和地克珠利对兔球虫都有一定的治疗效果。磺胺二甲嘧啶组与地克珠利组平均日增重分别为9.42~9.88和14.76~15.64 g,两组兔的每克粪便卵囊数量分别为4390~4770和1990~2500个,3组兔的存活率分别为80%、100%、10%。由此得出,地克珠利对促进兔增重、抑制球虫卵囊的产生与排出和提高兔存活率作用都显著优于磺胺二甲嘧啶。To investigate the therapeutic effect of sulfadimidine and diquizumil on rabbit coccidiosis.In this experiment,30 rabbits infected with coccidium rabbit in natural condition but with no significant difference in infection inmil group)and C group(blank control group),with 10 rabbits in each group.Sulfadimidine 500 mg/kg was added to the drinking water of the Agroup,and dicrozumil 2 mg/kg was added to the feed of the B group for consecutive 7 days,and then the animals were fed with conventional diet until the end of the experiment.The C group was fed with conventional feed as the control group with normal drinking water.The average amount of ovulation,average weight gain and survival rate after treatment were used as the main basis to judge the efficacy of drug therapy.The results showed that both sulfadimidine and dioczumil had certain therapeutic effects on rabbit coccidiosis.The OPG of the sulfadimidine group and the dixumil group were 4390-4770 and 1990-2500,respectively.The average daily gain of the two groups respectively.It was concluded that dicrozumil was significantly better than sulfadimidine in promoting weight gain,inhibiting the production and discharge of coccidiococcal oocyts and improving the survival rate of rabbits.

关 键 词：磺胺二甲嘧啶 地克珠利 自然感染 兔球虫 效果 

分 类 号：S829.1[农业科学—畜牧学]