龙眼干制前后缓解小鼠疲劳作用的研究  

Anti-fatigue Effect of Dried and Fresh Longan on Endurance Swimming Capacity of Mice

作　　者：高慧颖[1] 姜帆[2] GAO Huiying;JIANG Fan(Institute of Agricultural Engineering Technology,Fujian Academy of Agricultural Sciences,Fuzhou 350003;Fruit Research Institute,Fujian Academy of Agricultural Sciences,Fuzhou 350013)

机构地区：[1]福建省农业科学院农业工程技术研究所,福州350003 [2]福建省农业科学院果树研究所,福州350013

出　　处：《中国农学通报》2022年第11期106-110,共5页Chinese Agricultural Science Bulletin

基　　金：福建省科技厅福建省属公益科研院所专项“龙眼类黑精评价与生物活性研究”(2020R1028001);“灵芝-龙眼干发酵产物的代谢组学分析及产品创制”(2021R10320010);福建省农业科学院青年英才计划“龙眼枇杷特异种质资源评价与创新利用”(C2017-04)。

摘　　要：研究龙眼干制前后缓解疲劳作用的差异。把ICR雄性小鼠按体重随机分成4组,每组10只,分别为空白对照组、阳性对照组、鲜龙眼组、龙眼干组。按0.2 mL/10 g的剂量连续灌胃21天,称量第1、7、14、21天灌胃1 h后小鼠的质量,测定第21天小鼠的力竭游泳时间、负重游泳后肝糖原、血尿素氮、血乳酸脱氢酶的含量。与空白对照组相比,龙眼干极显著延长小鼠的力竭游泳时间(P<0.01),提高肝糖原(P<0.01)、血乳酸脱氢酶(P<0.05)的含量,显著降低血尿素氮含量(P<0.05);鲜龙眼能显著延长小鼠的力竭游泳时间(P<0.05)、降低血尿素氮含量(P<0.05),极显著增加血乳酸脱氢酶含量(P<0.01)。龙眼干制前后均具有缓解疲劳的效果,龙眼干比鲜龙眼提供更多的糖原合成底物可能是缓解疲劳效果更优的原因之一。To explore the anti-fatigue effect of fresh and dried longan aril on mice,the mice were randomly divided into the control group,positive control group,fresh longan group and dried longan group by their weigh,and each group had 10 mice.During 21 days of gavage(0.2 mL/10 g),the mice body weight was observed on day 1,7,14,and 21.After 21 days,the anti-fatigue effect was investigated by measuring the time of exhaustive swimming,and the content of hepatic glycogen,blood urea nitrogen and lactate dehydrogenase after weight loaded swimming.The results showed that,there was no influence on mice body weight development.Compared with the control group,the dried longan aril could significantly prolong the exhaustive swimming time(P<0.01),increase hepatic glycogen content(P<0.01)and lactate dehydrogenase content(P<0.05),but significantly reduce blood urea nitrogen content(P<0.05),which was similar to the positive control group.At the same time,the fresh longan aril could significantly prolong exhaustive swimming time(P<0.05)and increase lactate dehydrogenase content(P<0.01),while reduce blood urea nitrogen content(P<0.05).The research indicates that longan can enhance anti-fatigue effect,and the dried aril is superior to the fresh aril,possibly due to its glucose content.

关 键 词：龙眼干 抗疲劳 力竭游泳时间 肝糖原 血乳酸脱氢酶 血尿素氮 

分 类 号：S859.84[农业科学—临床兽医学]