综合运动对老年衰弱影响效果的Meta分析  

Meta-analysis of the effect of comprehensive exercise on senile frailty

作　　者：简凤 王芳[2] 刘娟[2] 廖顺琪 钟秋润 李月 JIAN Feng(Chengdu University of Chinese Medicine,Chengdu 610075,China)

机构地区：[1]成都中医药大学 [2]成都中医药大学附属医院,四川成都610072

出　　处：《牡丹江医学院学报》2022年第2期69-73,共5页Journal of Mudanjiang Medical University

基　　金：四川省干部保健科研课题(2021-502);成都中医药大学附属医院科技发展基金(20HL10)。

摘　　要：目的探讨综合运动治疗老年性衰弱的影响效果,为老年性衰弱的非药物治疗提供依据。方法计算机检索CNKI、万方、CBM、PubMed、Cochrane Library、Embase、Web of Science等数据库中关于运动对衰弱老年人效果影响的相关研究,检索时限为建库至2021年3月。由两名研究者独立筛选文献,提取数据,采用Stata 15.1软件进行Meta分析。结果最终共纳入8篇随机对照试验,包括639例老年衰弱患者,其中干预组319例,对照组320例。Meta分析结果显示,与对照组(常规治疗护理或常规生活)相对比,综合运动干预后可有效改善身体机能(SPPB评分)[SMD=1.29,95%CI(0.74,1.83),P<0.01],平衡得分(Barthel指数)更高[SMD=0.57,95%CI(0.03,1.11),P<0.05],提高患者的肌肉力量(握力)[SMD=0.92,95%CI(0.04,1.80),P<0.05]和功能性步行能力[SMD=-1.76,95%CI(-3.00,-0.51),P<0.01]。结论现有证据表明,综合运动治疗能有效改善老年衰弱患者的平衡能力、握力及步行能力,提高身体机能。Objective To explore the effect of comprehensive exercise on senile frailty and to provide basis for non-drug treatment of senile frailty.Methods A computer search was conducted on CNKI,Wanfang,CBM,PubMed,Cochrane Library,Embase,Web of Science and other databases for related studies on the effects of exercise on frail elderly.The retrieval time was from the establishment of the database to March,2021.Two researchers independently screened the literature,extracted the data,and performed a meta-analysis using Stata 15.1 software.Results A total of 8 randomized controlled trials were included,including 639 elderly patients with frailty,319 in the intervention group and 320 in the control group.The results of the meta-analysis showed that combined exercise intervention significantly improved physical function(SPPB score)compared with the control group[SMD=1.29,95%CI(0.74,1.83),P<0.01],the balance score(Barthel)was higher[SMD=0.57,95%CI(0.03,1.11),P<0.05],the muscle strength(grip strength)[SMD=0.92,95%CI(0.04,1.80),P<0.05]and functional walking ability(TUG)[SMD=0.92,95%CI(0.04,1.80),P<0.05]were improved.Conclusion Existing evidence shows that comprehensive exercise therapy can effectively improve balance,grip strength and walking ability and improve physical function in frailty elderly.

关 键 词：综合运动 老年衰弱 随机对照试验 META分析 

分 类 号：R473[医药卫生—护理学]