TOF-MRA和ASL-MRA在体检人群颅内动脉MRI扫描中的对比应用研究  

Study of Intracranial Artery MRI Scanning in Physical Examination Population:Compare TOF-MRA with ASL-MRA

作　　者：乔文俊[1,2] 周芳 黄婵桃[1] 林洁[1] 李彩霞[1] 张梓雄[1] 严承功 许乙凯[1,2,3] QIAO Wen-jun;ZHOU Fang;HUANG Chan-tao;LIN Jie;LI Cai-xia;ZHANG Zi-xiong;YAN Cheng-gong;XU Yi-kai(Imaging Center,Nanfang Hospital,Southern Medical University,Guangzhou 510515,Guangdong Province,China;Guangdong Quality Control Center of Radiology,Guangzhou 510515,Guangdong Province,China;Key Laboratory of Mental Health of the Ministry of Education,Southern Medical University,Guangzhou 510515,Guangdong Province,China)

机构地区：[1]南方医科大学南方医院影像中心,广东广州510515 [2]广东省放射医学诊断质量控制中心,广东广州510515 [3]南方医科大学精神健康研究教育部重点实验室,广东广州510515

出　　处：《中国CT和MRI杂志》2022年第6期1-3,11,共4页Chinese Journal of CT and MRI

基　　金：教育部创新团队滚动项目(IRT_16R37)。

摘　　要：目的对比性评估TOF-MRA和ASL-MRA在体检人群颅内动脉的成像质量以及适应证。方法收集2020年5月至2021年6月于南方医科大学南方医院行头颅MRA检查的受检者489例,所有受检者同时行TOF-MRA和ASL-MRA扫描。由两名影像医师采用双盲法分别对TOF-MRA和ASL-MRA图像质量进行评分,并检验两位医师对两种MRA方法评分结果的一致性。根据颅内动脉是否有病变及病变类型,主要分为正常血管组、颅内动脉狭窄组、颅内动脉或椎动脉纤细组、颅内动脉闭塞组、颅内动脉瘤组,并对各组中两种MRA成像方法的评分进行对比分析。结果489例受检者中,正常血管326例、颅内动脉狭窄61例、颅内动脉或椎动脉纤细61例、颅内动脉闭塞18例、颅内动脉瘤17例、其余6例。两位医师TOF-MRA和ASL-MRA图像质量评分结果一致性良好。正常血管组TOF-MRA和ASL-MRA图像质量评分差异无统计学意义(P=0.963);颅内动脉狭窄组、颅内动脉瘤组的TOF-MRA评分低于ASL-MRA(P值均<0.001);颅内动脉或椎动脉纤细组、颅内动脉闭塞组的TOF-MRA评分高于ASL-MRA(P值均<0.05)。结论对于正常颅内血管,TOF-MRA和ASL-MRA均可提供高质量的图像,对存在狭窄、动脉瘤病变的血管,ASL-MRA可以提供更高的图像质量和更多的诊断信息,而对于闭塞、颅内动脉或椎动脉纤细的血管,TOF-MRA成像效果更优,望临床根据实际情况采取合适的扫描方法。Objective To investigate the image quality and clinical application value of TOF-MRA and ASL-MRA in the intracranial arteries of the physical examination population comparatively.Methods 489 patients with head MRA examinations at Nanfang Hospital of Southern Medical University were collected from May 2020 to June 2021.All the patients scaned both TOF-MRA and ASL-MRA sequences.Scores would be given by two experienced radiologist with a double-blind method and be tested the consistency.According to whether there are lesions and the types of intracranial arteries,they are mainly divided into normal arteries group,intracranial artery stenosis group,intracranial artery or vertebral artery slender group,intracranial artery occlusion group,and intracranial aneurysm group,and then compare the image scores of the two MRA imaging methods in each group.Results Among the 489 patients,326 with normal arteries,98 with stenosis of intracranial arteries,61 with slender intracranial arteries or vertebral arteries,18 with occlusions of intracranial arteries,and 17 with intracranial aneurysms.The TOF-MRA and ASL-MRA image quality scores of the two radiologists were in good agreement.The TOF-MRA and ASL-MRA image quality scores of the normal vascular group were not statistically different(P=0.963).The TOF-MRA scores of the intracranial artery stenosis group and the intracranial aneurysm group were lower than ASL-MRA(P<0.001).The TOF-MRA scores of intracranial artery or vertebral artery slender group,intracranial artery occlusion group was higher than the ASL-MRA(P<0.05).Conclusion For normal intracranial vessels,both TOF-MRA and ASL-MRA can provide highquality images.ASL-MRA can provide higher image quality and more diagnostic information in stenosis and aneurysm disease,while TOF-MRA imaging effect is better for occluded or slender blood vessels.It is suggested that we should adopt appropriate scanning methods according to the actual situation.

关 键 词：TOF-MRA ASL-MRA 颅内动脉 成像质量 

分 类 号：R651.1[医药卫生—外科学]