MR预测不同质地垂体腺瘤可靠性及其与胶原含量相关性研究  被引量:5

Reliability of MR Prediction of Pituitary Adenomas with Different Textures and Its Correlation with Collagen Content

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作  者:郭强[1] 翟海程[1] 蒋继虎 GUO Qiang;ZHAI Hai-cheng;JIANG Ji-hu(Department of Neurosurgery,Hanzhong Central Hospital,Hanzhong 723000,Shaanxi Province,China)

机构地区:[1]汉中市中心医院神经外科,陕西汉中723000

出  处:《中国CT和MRI杂志》2022年第6期26-28,共3页Chinese Journal of CT and MRI

基  金:陕西省卫生健康科研基金项目(2018D158)。

摘  要:目的探讨MR预测不同质地垂体腺瘤可靠性及其与胶原含量相关性。方法选取本院2018年4月至2020年2月收治且经手术病理确诊的62例垂体腺瘤患者作为研究对象,分析MRI信号不同垂体腺瘤质地及其胶原总含量的相关性。结果不同质地垂体腺瘤T_(1)WI/白质信号比值无明显差异(P>0.05);T_(2)WI/白质与T_(2)WI/脑桥信号比值以质地软瘤体最高,质地硬瘤体最低,三组T_(2)WI/白质、T_(2)WI/脑桥信号比较差异具有统计学意义(P<0.05)。质地软的垂体腺瘤其平均胶原含量为(2.42±0.98)%,质地中等垂体腺瘤胶原含量为(7.24±1.12)%,质地硬垂体腺瘤胶原含量为(17.97±1.07)%,质地硬瘤体胶原含量显著高于质地软、中等瘤瘤体,三组胶原含量比较差异显著(F=931.08,P<0.001)。T_(2)WI肿瘤白质信号与垂体腺瘤胶原总含量均呈负相关(P<0.05)。结论T_(2)WI可反映肿瘤内胶原含量,白质信号与垂体腺瘤胶原总含量均呈负相关,根据信号值可有效评估肿瘤质地。Objective To explore the reliability of MR prediction of pituitary adenomas with different textures and its correlation with collagen content.Methods 62 patients with pituitary adenomas diagnosed by surgery and pathology who were treated in our hospital from April 2018 to February 2020 were selected as the research subjects,and the correlation between the texture of different pituitary adenomas displayed by MRI signals and their total collagen content was analyzed.Results There was no significant difference in T_(1)WI/white matter signal ratio between pituitary adenomas with different texture(P>0.05).The ratios of T_(2)WI/white matter and T_(2)WI/pontine signals were highest in soft tumors and the lowest in hard tumors.The differences in T_(2)WI/white matter and T_(2)WI/pontine signals between the three groups were statistically significant(P<0.05).The average collagen content of pituitary adenoma with soft texture is(2.42±0.98)%,the content of collagen of pituitary adenoma with medium texture is(7.24±1.12)%,and the content of collagen of pituitary adenoma with hard texture is(17.97±1.07)%.The content of collagen of pituitary adenoma with hard texture was significantly higher than that in pituitary adenoma with soft and soft texture.The three groups had significant differences in collagen content(F=931.08,P<0.001).The white matter signal of T_(2)WI tumors was negatively correlated with the total collagen content of pituitary adenomas(P<0.05).Conclusion T_(2)WI can reflect the collagen content in the tumor,and the white matter signal has a negative correlation with the total collagen content of the pituitary adenoma.According to the signal value,the tumor texture can be effectively evaluated.

关 键 词:MRI检查 垂体腺瘤 胶原蛋白 肿瘤质地 

分 类 号:R445.2[医药卫生—影像医学与核医学] R736.4[医药卫生—诊断学]

 

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