双源CT冠状动脉钙化积分及腹主动脉钙化评分与Ⅲ-Ⅴ期慢性肾功能不全的相关性分析  

Correlation Analysis of Coronary Artery Calcification Score of Dual-Source CT,Abdominal Aortic Calcification Score and StageⅢ-ⅤChronic Renal Disease

作　　者：康男男 林禹 岳鑫[1] 何金选[2] 王金岸[1] KANG Nan-nan;LIN Yu;YUE Xin;HE Jin-xuan;WANG Jin-an(Department of Radiology,Zhongshan Hospital Affiliated to Xiamen University,Xiamen 361000,Fujian Province,China;Department of Nephrology,Zhongshan Hospital Affiliated to Xiamen University,Xiamen 361000,Fujian Province,China)

机构地区：[1]厦门大学附属中山医院影像科,福建厦门361000 [2]厦门大学附属中山医院肾内科,福建厦门361000

出　　处：《中国CT和MRI杂志》2022年第6期98-100,共3页Chinese Journal of CT and MRI

基　　金：厦门市科技计划项目(3502Z20174081)。

摘　　要：目的探讨双源CT冠状动脉钙化积分(CaCS)和腹主动脉钙化评分(AACS)与Ⅲ~Ⅴ期慢性肾功能不全(CKD)的相关性。方法回顾性分析63例Ⅲ~Ⅴ期CKD患者。所有患者均行双源CT及腹部侧位X平片检查。测量冠状动脉各分支的CaCS值、总CaCS值及AACS值。采用Kruskal-Wallis检验、χ^(2)检验或Fisher精确检验评价各指标差异。采用Spearman相关性分析评价不同期CKD与CaCS的相关性。结果随着CKD的进展,总CaCS也随之显著增加(P<0.05)。不同期CKD与冠状动脉钙化的发生率(r=0.53,P=0.000)、多支冠状动脉血管钙化的发生率(r=0.32,P=0.01)均呈正相关;不同期CKD的冠状动脉钙化更好发于LAD、LCX及RCA,其钙化的发生率与CKD分期呈正相关(P<0.05)。结论Ⅲ~Ⅴ期CKD与CaCS的密切相关。随着CKD的进展,冠状动脉钙化发生率越高,累及的范围更广。Objective To explore the correlation between dual-source CT coronary artery calcification score(CaCS),abdominal aortic calcification score(AACS)and chronic kidney disease(CKD)at stageⅢ-Ⅴ.Methods 63 cases of stageⅢ-ⅤCKD were retrospectively reviewed.All patients underwent dual-source CT and lateral abdominal X-ray examination.The CaCS value of each branch of coronary artery,total CaCS value,and AACS value were measured.The Kruskal-Wallis test,Chi-square test or Fisher's exact test were used to evaluate the difference of each index.Spearman correlation analysis was used to evaluate the correlation between different stages CKD and coronary artery calcification.Results As CKD progressed,total CaCS also significantly increased(P<0.05).CKD in different stages was positively correlated with the incidence of coronary vascular calcification(r=0.53,P=0.000)and multivessel calcification(r=0.32,P=0.01).Compared with LM calcification,coronary calcification of CKD at different stages was more common in LAD,LCX and RCA.The incidence of calcification is positively correlated with CKD stage(P<0.05).Conclusion StageⅢ-ⅤCKD is strongly relevant to CaCS;With the progress of CKD,the incidence of coronary calcification is higher and the range of involvement is wider.

关 键 词：慢性肾功能不全 冠状动脉钙化积分 双源CT 

分 类 号：R445.3[医药卫生—影像医学与核医学] R714.252[医药卫生—诊断学]