小儿细菌感染性腹泻病原菌分布特点及耐药性分析  

Distribution and Drug Resistance of Pathogens in Children with Bacterial Infectious Diarrhea

作　　者：史运强 SHI Yun-qiang(Department of Pediatrics,Fanxian People's Hospital,Puyang 457500,Henan Province,China)

机构地区：[1]范县人民医院儿科,河南濮阳457500

出　　处：《罕少疾病杂志》2022年第6期96-98,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的分析小儿细菌感染性腹泻病原菌分布特点及耐药性情况。方法选择我院2018年10月至2020年10月收治的感染性腹泻患儿728例,采集患儿新鲜大便样本培养,并进行药敏试验。统计分析粪便培养和药敏试验结果。结果728份腹泻患儿粪便标本中共分离出病原菌63株,检出率8.65%,主要病原菌包括志贺菌属(10株)、大肠埃希菌(8株)、沙门菌属(7株)、变形杆菌属(7株)、肠球菌属(7株)。药敏试验显示,以上5种主要病原菌中,以亚胺培南敏感性最好,其次是头孢哌酮、头孢曲松。结论小儿细菌感染性腹泻病原菌以格兰阴性菌为主,临床治疗应合理使用抗生素,避免产生耐药性。Objective To analyze the distribution characteristics and drug resistance of pathogenic bacteria in children with bacterial infectious diarrhea.Methods From October 2018 to October 2020,728 children with infectious diarrhea in our hospital were selected as the research objects.Fresh stool samples were collected and cultured,and drug sensitivity test was carried out.The results of fecal culture and drug sensitivity test were statistically analyzed.Results A total of 63 strains of pathogenic bacteria were isolated from 728 stool samples of children with diarrhea,with a detection rate of 8.65.The main pathogenic bacteria included Shigella(10 strains),Escherichia coli(8 strains),Salmonella(7 strains),Proteus(7 strains),Enterococcus(7 strains).Drug sensitivity test showed that among the five main pathogens,imipenem was the most sensitive,followed by cefoperazone and ceftriaxone.Conclusion Gram negative bacteria are the main pathogens in children with bacterial infectious diarrhea.Antibiotics should be used reasonably in clinical treatment to avoid drug resistance.

关 键 词：感染性腹泻 药敏试验 病原菌分布特点 耐药性 

分 类 号：R442.2[医药卫生—诊断学]