磁性纳米颗粒负载磺酸-磷钨酸型双杂化催化剂的合成及其催化性能研究  

Synthesis of Sulfonic Acid-Phosphotungstic Acid Double-Hybrid Catalyst Supported on Magnetic Nanoparticles and Its Catalytic Performance

作　　者：王理想 冯菊红[1,2] 张朵朵 陈雅婷 盛余豪 汪涛 胡学雷[1,2] WANG Lixiang;FENG Juhong;ZHANG Duoduo;CHEN Yating;SHENG Yuhao;WANG Tao;HU Xuelei(School of Chemical Engineering and Pharmacy,Wuhan Institute of Technology ,Wuhan 430074,China;Key Laboratory for Green Chemical Process of Ministry of Education,Wuhan 430074,China)

机构地区：[1]武汉工程大学化工与制药学院,湖北武汉430074 [2]绿色化工过程教育部重点实验室,湖北武汉430074

出　　处：《化学与生物工程》2022年第5期17-21,共5页Chemistry & Bioengineering

基　　金：湖北省自然科学基金重点项目(2011CDA048)。

摘　　要：基于二氧化硅包覆的四氧化三铁磁性纳米颗粒,合成了一种新型的磺酸-磷钨酸型双杂化催化剂,通过FTIR、XRD、SEM等对其进行表征,将该催化剂用于催化二氢吡喃并[2,3-c]吡唑类化合物的多组分合成,并优化了合成条件。结果表明,该催化剂具有较高的催化活性,在乙醇-水(1∶1,体积比)为反应溶剂、反应温度为50℃、催化剂用量为50 mg、反应时间为20 min的最佳条件下,6-氨基-4-苯基-3-甲基-2,4-二氢吡喃并[2,3-c]吡唑-5-腈收率可达92%。此外,该催化剂重复使用6次后,催化活性并没有明显损失。We synthesized a novel sulfonic acid-phosphotungstic acid double-hybrid catalyst on the basis of silica coated ferroferric oxide magnetic nanoparticles,and characterized the catalyst by FTIR,XRD,and SEM.Moreover,we adopted the catalyst to catalyze the multi-component synthesis of dihydropyrano[2,3-c]pyrazoles,and optimized the synthesis conditions.The results show that the catalyst has high catalytic activity,and the yield of 6-amino-4-phenyl-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-nitrile can reach 92%under the optimal conditions as follows:ethanol-water(1∶1,volume ratio)is adopted as the reaction solvent,the reaction temperature is 50℃,the catalyst dosage is 50 mg,and the reaction time is 20 min.In addition,the catalyst can keep high catalytic activity after being reused for 6 times.

关 键 词：磁性纳米颗粒 双杂化催化剂 磷钨酸 多组分反应 

分 类 号：TQ426.97[化学工程] O643.36[理学—物理化学]