Drying Technology and Formation Process of Naomai Xingshen Capsules  

作　　者：Congyan ZENG Yu ZHANG Bin ZHUO Shi LIANG Yuliang HU 

机构地区：[1]Zhongshan Hospital of Traditional Chinese Medicine, Affiliated to Guangzhou University of Chinese Medicine, Zhongshan 528400, China

出　　处：《Medicinal Plant》2022年第2期8-11,共4页药用植物：英文版

基　　金：Medical Research Project of Zhongshan City Health and Family Planning Bureau,Guangdong Province(2015J050).

摘　　要：[Objectives]To optimize the drying technology and formation process of Naomai Xingshen Capsules.[Methods]The yield of paste powder and moisture content as evaluation indicators were taken as indicators,the relative density of feed liquid,inlet air temperature and dosage of excipients were selected as investigation factors,the orthogonal experiment method was used to optimize the spray drying process.The moisture absorption rate and angle of repose were taken as evaluation indicators,the types of forming excipient were screened,and the critical relative humidity was determined.[Results]The optimum spray drying process was that the relative density of liquid medicine was 1.05(60℃),the air inlet temperature was 200℃,and the dosage of excipients was 2%.The effect of using dextrin as a forming excipient was better,and the relative humidity of the production environment should be controlled below 65%.[Conclusions]The optimized process is stable,feasible,scientific and reasonable,and can be used for large-scale industrial production.

关 键 词：Naomai Xingshen Capsules Orthogonal experiment SPRAY-DRYING Forming process Angle of repose Moisture absorption rate Critical relative humidity 

分 类 号：TG1[金属学及工艺—金属学]