贺氏火针治疗功能性消化不良脾胃虚寒证临床研究  

Evaluation of the treatment of functional dyspepsia of deficiency cold of spleen and stomach by He Style fire acupuncture

作　　者：丁洋[1] 张声生[1] 王鹏[2] 陈鹏[2] 孟梦[1] 罗晔 程海英[2] 刘赓[1] Ding Yang;Zhang Shengsheng;Wang Peng;Chen Peng;Meng Meng;Luo Ye;Cheng Haiying;Liu Geng(Digestive Disease Center,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;Acupucture Center,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;Department of Traditional Chinese Medicine,Zhongshan Hospital Affiliated to Xiamen University,Xiamen 361000,China)

机构地区：[1]首都医科大学附属北京中医医院消化中心,北京100010 [2]首都医科大学附属北京中医医院针灸中心,北京100010 [3]厦门大学附属中山医院中医科,厦门361000

出　　处：《国际中医中药杂志》2022年第3期263-267,共5页International Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(81400560);北京市自然科学基金(7164265);北京市属医院科研培育计划项目(PZ2021020, PZ2022014);北京中医医院院级课题暨两院合作课题资助项目(YJ-201713)。

摘　　要：目的评价贺氏火针治疗功能性消化不良脾胃虚寒证患者的临床疗效。方法选择2017年3月-2019年3月首都医科大学附属北京中医医院功能性消化不良脾胃虚寒证患者60例, 在研究过程中自然形成2个队列, 分别暴露在2种不同的干预措施中, 其中对照组30例口服莫沙必利片, 治疗组30例在对照组基础上结合火针点刺治疗。2组均治疗4周, 随访1个月。分别于治疗前后进行临床症状评分, 采用健康状况相关生活质量量表(SF-36)评价患者生活质量, 记录治疗期间的不良事件, 评价临床疗效。结果治疗组总有效率为93.3%(28/30)、对照组为76.7%(23/30), 2组比较差异有统计学意义(χ^(2)=4.78, P<0.05)。治疗组治疗后上腹痛、上腹部烧灼感、餐后饱胀不适、早饱感评分及总分低于对照组(t值分别为4.27、5.16、3.93、4.69、4.28, P值均<0.05), 随访时上腹痛、上腹部烧灼感、餐后饱胀不适评分及总分低于对照组(t值分别为3.63、3.22、4.03、3.04, P值均<0.05)。治疗组治疗后生理功能、生理职能、精神健康、健康变化评分高于对照组治疗后(t值分别为2.97、4.05、4.22、3.05, P值均<0.05), 随访时生理功能、生理职能、躯体疼痛、总体健康、生命活力、精神健康、健康变化评分高于对照组(t值分别为3.27、4.23、3.85、3.15、3.25、6.15、3.85, P值均<0.05)。结论贺氏火针结合莫沙必利片可有效改善功能性消化不良脾胃虚寒证患者上腹痛及上腹部烧灼感等症状, 提高生活质量与临床疗效。Objective To observe the curative effect of He Style fire acupuncture on functional dyspepsia of deficiency cold of spleen and stomach syndrome.Methods Sixty patients who met the inclusion criteria from March 2017 to March 2019 in Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University were divided into 2 groups according to the random number table method,with 30 in each group.The control group was given mosapride tablets,one tablet(5 mg)each time half an hour before meals.On the basis of the control group,the treatment group was given fire acupuncture on Zusanli(ST36),Zhongwan(CV12),Pishu(BL20),Weishu(BL21),Guanyuan(CV4)and Qihai(CV6)twice a week.The course of treatment for both groups of patients was 4 weeks.A follow-up was visited at 1 month after the treatment.The total Symptom Scores and Health-Related Quality of Life Scale(SF-36)scores were performed before and after treatment,and the total scores of syndromes of patients with Deficiency cold of spleen and stomach before and after treatment were used for clinical efficacy evaluation,and adverse events during treatment were recorded.Results The total efficiency of the treatment group was 93.3%(28/30),and 76.7%(23/30)in the control group,and the 2 groups were statistically significant(χ^(2)=4.78,P<0.05).After treatment,the upper abdominal pain,upper abdominal burning,postprandial fullness and discomfort,early satiety,and total scores in the treatment group were significantly lower than those in the control group(t values were 4.27,5.16,3.93,4.69,4.28,respectively,all Ps<0.05);during follow-up,the upper abdominal pain,upper abdominal burning,postprandial fullness and discomfort and the total scores in the treatment group were significantly lower than those in the control group(t values were 3.63,3.22,4.03,3.04,respectively,all Ps<0.05).In terms of SF-36,after treatment,the treatment group showed significantly higher scores in the control group of physical function,physiology,mental health,and health changes compared with the

关 键 词：消化不良 火针疗法 贺氏火针 脾胃虚寒证 

分 类 号：R246.1[医药卫生—针灸推拿学]