LED光疗仪在皮肤中的穿透评估  

Evaluation of light penetration of LED phototherapy apparatus in skin

作　　者：冯泽峰 王沛沛[2] 杨旭[1,2] 刘虎 熊大曦[2] FENG Zefeng;WANG Peipei;YANG Xu;LIU Hu;XIONG Daxi(School of Biomedical Engineering(Suzhou),Division of Life Sciences and Medicine,University of Science and Technology of China,Suzhou 215163,China;Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Science,Suzhou 215163,China)

机构地区：[1]中国科学技术大学生物医学工程学院(苏州),江苏苏州215163 [2]中国科学院苏州生物医学工程技术研究所,江苏苏州215163

出　　处：《光学精密工程》2022年第10期1139-1150,共12页Optics and Precision Engineering

基　　金：国家重点研发计划项目(No.2018YFC0114800);国家自然科学基金面上项目(No.51376191);苏州市重点产业技术创新项目(No.SYG202035)。

摘　　要：基于LED光源的低强度光治疗(LLLT)是一项快速发展的非侵入式光治疗技术。相比于激光,LED光疗能轻易产生较大面积的治疗光斑,并且获得与激光几乎一致的治疗效果。在LED光疗仪设计及光疗方案制定时,考虑到边缘光线与皮肤间角度过大会影响光的穿透效果,因此需要一个皮肤模型分析大面积光斑时的光穿透情况。首先,本论文根据皮肤组织的光学特性建立了一个通用的皮肤模型样本。然后,利用蒙特卡洛模拟方法对LED光源发出的光进行追迹,并分析了不同波长、不同发散角的光,在该样本中的光分布和能量吸收情况。最后,根据人体肩部、前臂背侧、臀部三个部位皮肤的参数,与样本模型进行对照,验证模型的可靠性。模拟的最终结果给出了大尺寸LED光斑在皮肤中的传输情况,并且在不同部位皮肤的模拟实验中,均得到需要将光斑发散半角控制在30°以内的结论,为LED光治疗领域提供了重要参考。Low-level light therapy(LLLT)based on light-emitting diode(LED)light sources is a rapidly-developing and non-invasive light therapy technology.In contrast to a laser,LED phototherapy can easily produce a larger treatment spot area,while achieving almost the same treatment effect.When designing LED phototherapy equipment and formulating phototherapy plans,too large an angle between the edge light and skin could affect the light penetration effect.Therefore,a skin model is required to analyze the light penetration for a large area of light spots.First,this study identified a general skin model sample based on the optical properties of skin tissue.Then,Monte Carlo simulation was used to trace the light emitted by the LED light source,and the wavelength distribution of light and different divergence angles were analyzed.Finally,the reliability of the sample model was verified based on the skin parameters of the human shoulder,forearm back,and buttocks.The simulation results demonstrated the transmission of a large-sized LED spot in the skin.Experimental simulations of different skin parts proved that the spot di⁃vergence half-angle needs to be controlled within 30°.This provides an important reference for the field of LED light therapy.

关 键 词：LED光疗 低强度光治疗 皮肤模型 蒙特卡洛模拟 光发散角 光穿透 

分 类 号：TB133[机械工程—光学工程]