新型冠状病毒肺炎与成人支原体肺炎的临床特征比较  

Comparison of the Clinical Characteristics between Coronavirus Disease 2019(COVID-19)and Adult Mycoplasma Pneumonia

作　　者：郑玲 伍定辉[1] ZHENG Ling;WU Dinghui(Department of Pulmonary Medicine, Xinglin Branch of The First Affiliated Hospital of Xiamen University, Xiamen 361003,China)

机构地区：[1]厦门大学附属第一医院杏林分院肺科,厦门361003

出　　处：《福建医科大学学报》2022年第2期132-135,共4页Journal of Fujian Medical University

摘　　要：目的比较新型冠状病毒肺炎(COVID-19)与成人支原体肺炎的临床特征,帮助临床医师尽早发现及确诊COVID-19。方法回顾性分析35例COVID-19患者和28例成人支原体肺炎患者的临床表现、实验室指标及影像学数据资料。结果COVID-19患者和成人支原体肺炎患者发热、乏力、咳痰、咽痛等发生率比较,差别无统计学意义(P>0.05),但COVID-19患者多表现为年龄更大,伴有更低的白细胞数、淋巴细胞数、中性粒细胞数及C-反应蛋白(CRP)(P<0.05)。影像学上,97.1%的COVID-19患者为双肺受累,且受累肺叶多于成人支原体肺炎患者(P<0.05),特征上多表现为片絮状、斑片样及磨玻璃样改变,部分为结节影或浸润影。流行病学史、聚集性特点也有助于鉴别二者。结论COVID-19和成人支原体肺炎患者具有相似的临床表现,通过询问流行病学史,结合血常规、CRP及影像学表现有助于鉴别。Objective To compare the clinical characteristics differences in adult patients with coronavirus disease 2019(COVID-19)and Mycoplasma pneumonia,to help the clinicians to detect and confirm COVID-19 as early as possible.Methods The clinical data including clinical symptoms,laboratory parameters and chest CT imaging features in 35 adult patients with COVID-19 and 28 adult patients with Mycoplasma pneumonia were retrospectively analyzed.Results There were no significant differences(P>0.05)in the incidence of fever,fatigue,expectoration and sore throat between the adults patients with COVID-19 and adults patients with Mycoplasma pneumonia.Adult patients with COVID-19 were characterized with older age,lower white blood cell,lower lymphocyte,lower neutrophil granulocyte and lower C reactive protein(CRP)(P<0.05).As high as 97.1%of the abnormal CT findings were distributed in bilateral lungs in COVID-19 patients.And more lung lobes involved were found in adult patients with COVID-19 when compared with those in Mycoplasma pneumonia group(P<0.05).Meantime,the abnormalities on CT including flocculent exudation shadow,patch consolidation,pulmonary ground-glass opacity,nodules or infiltrates were found in adult patients with COVID-19.In addition,epidemiological history and clustering cases were also helpful for the diagnosis of COVID-19.Conclusion Although adult patients with COVID-19 and Mycoplasma pneumonia had similar clinical manifestations,it would be helpful to identify COVID-19 by collecting epidemiological history,combining with the changes in hemogram,CRP and chest CT imaging.

关 键 词：新型冠状病毒肺炎 支原体肺炎 临床特征 

分 类 号：R72[医药卫生—儿科]