革兰阳性球菌与肠杆菌科细菌所致儿童肺部感染的临床特征比较  

Comparison of Clinical Characteristics of Pulmonary Infections in Children Caused by Gram-positive Cocci and Enterobacteriaceae

作　　者：刘倩 张飞雨 刘明峰[3] 李军涛 邵毅 闫成 苏彦雷 LIU Qian;ZHANG Fei-yu;LIU Ming-feng;LI Jun-tao;SHAO Yi;YAN Cheng;SU Yan-lei(Department of Geriatrics,Youfu Hospital of Hebei Province,Shijiazhuang 050051,China;the First Central Clinical College of Tianjin Medical University,Tianjin 300192,China;Department of Pharmacy,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China;the 980th Hospital of PLA Logistics Support Forces,Department of Clinical Laboratory,Shijiazhuang 050082,China;the 980th Hospital of PLA Logistics Support Forces,Department of Pediatrics,Shijiazhuang 050082,China;the 980th Hospital of PLA Logistics Support Forces,Department of Clinical Pharmacy,Shijiazhuang 050082,China)

机构地区：[1]河北省优抚医院老年病科,石家庄050051 [2]天津医科大学一中心临床学院,天津300192 [3]河北医科大学第四医院药学部,石家庄050011 [4]解放军联勤保障部队第九八〇医院检验科,石家庄050082 [5]解放军联勤保障部队第九八〇医院儿科,石家庄050082 [6]解放军联勤保障部队第九八〇医院临床药学科,石家庄050082

出　　处：《解放军医药杂志》2022年第5期49-51,共3页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：河北省卫生健康委科研课题项目(20191055)。

摘　　要：目的比较革兰阳性球菌与肠杆菌科细菌所致儿童肺部感染的临床特征差异。方法回顾性分析2020年12月—2021年2月革兰阳性球菌(n=35)与肠杆菌科细菌(n=19)所致肺部感染患儿的临床资料。结果革兰阳性球菌组患儿与肠杆菌组相比,在最高体温、白细胞计数、中性粒细胞绝对值、中性粒细胞百分比、淋巴细胞百分比方面差异有统计学意义(P<0.05)。淋巴细胞百分比是预测感染革兰阳性球菌的独立危险因素(P<0.05)。结论革兰阳性球菌与肠杆菌科细菌所致儿童肺部感染的临床特征存在差异,可为病原学不明情况下患儿临床抗感染治疗中的抗菌药物选择提供参考。Objective To compare the differences in the clinical characteristics of pulmonary infections in children caused by gram-positive cocci and Enterobacteriaceae bacteria and to provide assistance in the selection of antimicrobial drugs for children with pulmonary infections of unknown etiology.Methods The clinical data of children with pulmonary infection caused by gram-positive cocci(n=35)and Enterobacteriaceae bacteria(n=19)from December 2020 to February 2021 was analyzed retrospectively.Results There were significant differences in the highest body temperature,absolute value of leukocytes,neutrophils,percentage of neutrophils and percentage of lymphocytes between children in gram-positive cocci group and Enterobacteriaceae bacteria group(P<0.05).The percentage of lymphocytes was an independent risk factor for predicting the infection of gram-positive cocci(P<0.05).Conclusion There are differences in the clinical characteristics of pulmonary infection in children caused by gram-positive cocci and Enterobacteriaceae bacteria,which can provide a reference for the selection of antibiotics in clinical anti-infection treatment in children with pulmonary infections of unknown etiology.

关 键 词：革兰阳性球菌 肠杆菌属 肺部感染 临床特征 淋巴细胞 

分 类 号：R725.631[医药卫生—儿科]