AMS模式推进临床抗菌药物合理应用的效果评价  

AMS Mode to Promote The Rational Application Evaluation of Clinical Antibiotics

作　　者：吴丽芳 林涛 付婴子 陈文瑜 WU Li-fang;LIN Tao;FU Ying-zi;CHEN Wen-yu(Department of Pharmacy,Second Hospital of Xiamen,Xiamen 361021,China)

机构地区：[1]厦门医学院附属第二医院药学部,福建厦门361021

出　　处：《海峡药学》2022年第5期101-104,共4页Strait Pharmaceutical Journal

基　　金：厦门市科技局资助项目(3502Z20194063 AMS模式推进临床抗感染合理应用的效果评价)。

摘　　要：目的构建抗菌药物管控的新模式,探索形成长效的管理机制。方法将六西格玛管理的定义、测量、分析、改进和控制五步法应用到AMS模式,识别管控最关键的影响因素,并针对性采取改进措施。比较2018年至2021年9月六西格玛应用前后的相关评价指标。结果应用管控新模式后,抗菌药物合理使用率、微生物标本送检率逐年提升,住院患者人均药费及抗菌药费显著降低,而平均住院天数差异无统计学意义。结论AMS模式下的六西格玛管理模式可促进临床抗菌药物合理使用,相关经验可为各医疗机构提供参考。OBJECTIVE To explore the long-term mechanism of antibacterial drug use by establishing a new management model.METHODS Five phases of Six-Sigma(define,measure,analyze,improve and control)were used to find out the key factors that affected AMS,targeted improvement measures were taken.The data from 2018 to 2021 September were analyzed before and after adopting Six-Sigma was compared.RESULTS After applying management model for antibacterial drug use,the rational use rate of antibiotics and the submission rate of microbial samples increased year by year;the per capita drug cost and antibacterial drug cost of inpatients decreased significantly,but the difference in average hospitalization days was not statistically significant.CONCLUSION Six Sigma management model under AMS model can promote rational use of antibiotics,and relevant experience can provide reference for medical institutions.

关 键 词：六西格玛 抗菌药物 科学化管理 合理用药 

分 类 号：R969.4[医药卫生—药理学]