左氧氟沙星联合氯诺昔康致肌痛1例  

One Case of Myalgia Caused by Levofloxacin Combined with Lornoxicam

作　　者：朱春梅 ZHU Chun-mei(Dept.of Pharmacy,Putian Medical District of the 900th Hospital of the Joint Service Support Force of PLA,Putian 351100,China)

机构地区：[1]联勤保障部队第九○○医院莆田医疗区药学科临床药学室,福建莆田351100

出　　处：《海峡药学》2022年第5期135-136,共2页Strait Pharmaceutical Journal

摘　　要：目的通过对肺炎患者肌酸激酶(CK)升高、肌痛原因的分析,从用药方面探讨引起的原因。方法回顾性分析1例肺炎患者的临床资料,从患者入院前到入院后所用药物分析引起CK升高、肌痛的原因。结果患者入院时即发现CK升高,入院后出现肌痛,与院外联合使用的左氧氟沙星和氯诺昔康关联性大。结论对于使用喹诺酮类药物的患者,特别是与其他药物联用,要注意相关的肌肉不良反应,如出现CK升高伴肌肉疼痛症状,要怀疑可能发生横纹肌溶解症,需要立即停药并处理。OBJECTIVE To analyze the causes of increased chiacid kinase(CK)and myalgia in patients with pneumonia,and to explore the causes from the aspect of medication.METHODS Reviewing the clinical data of 1 patient with pneumonia,and analyze the causes of CK elevation and myalgia from the aspect of medication before the patient′s admission and after.RESULTS CK was increased once the admission and myalgia was observed after admission,which was strongly related to levofloxacin and lornoxicam used in combination outside the hospital.CONCLUSION For patients using quinolones,especially in combination with other drugs,it is necessary to pay attention to related muscle adverse reactions,such as increased CK accompanied by muscle pain symptoms.It is suspected that rhabdomyolysis may occur,and should stop tating quinolones immediately and treat properly.

关 键 词：肌酸激酶 肌痛 左氧氟沙星 氯诺昔康 

分 类 号：R969.3[医药卫生—药理学]