腹腔镜与开腹穿孔修补术治疗胃十二指肠溃疡急性穿孔患者的效果比较  

Comparison of effect of laparoscopic and open perforation repair in the treatment of acute perforation of gastroduodenal ulcer

作　　者：于振强 YU Zhen-qiang(Central Hospital of Faku County,Shenyang 110499,China)

机构地区：[1]辽宁省沈阳市法库县中心医院,110499

出　　处：《中国现代药物应用》2022年第6期33-35,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨腹腔镜与开腹穿孔修补术治疗胃十二指肠溃疡急性穿孔患者的效果。方法90例胃十二指肠溃疡急性穿孔患者,按照数字表法分为观察组和对照组,每组45例。对照组采用常规开腹穿孔修补术治疗,观察组采用腹腔镜穿孔修补术治疗。比较两组患者治疗后胃肠功能恢复情况以及治疗前后炎性因子水平。结果观察组首次排气时间(15.35±2.01)h、首次排便时间(38.23±2.16)h及恢复正常肠鸣音时间(13.24±2.56)h均短于对照组的(32.24±2.13)、(53.15±1.23)、(25.12±2.30)h,差异具有统计学意义(P<0.05)。治疗后,观察组患者C反应蛋白(CRP)、白细胞介素-6(IL-6)以及肿瘤坏死因子-α(TNF-α)水平分别为(12.13±2.05)mg/L、(5.21±1.20)pg/ml、(21.23±2.03)ng/ml,均低于对照组的(19.22±2.03)mg/L、(10.26±2.14)pg/ml、(39.25±2.10)ng/ml,差异具有统计学意义(P<0.05)。结论在治疗胃十二指肠溃疡急性穿孔中采用腹腔镜与开腹穿孔修复术治疗,可以改善胃肠功能指标,促进恢复,改善临床炎性因子,维持正常指标。Objective To discuss the effect of laparoscopic and open perforation repair in the treatment of acute perforation of gastroduodenal ulcer.Methods A total of 90 patients with acute perforation of gastroduodenal ulcer were divided into observation group and control group according to the digital table method,with 45 cases in each group.The control group was treated with conventional laparoscopic perforation repair,while the observation group was treated with laparoscopic perforation repair.The recovery of gastrointestinal function and the levels of inflammatory factors before and after treatment were compared between the two groups.Results The first exhaust time(15.35±2.01)h,first defecation time(38.23±2.16)h and recovery time of bowel sounds(13.24±2.56)h in the observation group were all shorter than(32.24±2.13),(53.15±2.13),and(25.12±2.30)h in the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of C-reactive protein(CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in the observation group were(12.13±2.05)mg/L,(5.21±1.20)pg/ml,and(21.23±2.03)ng/ml,which were lower than(19.22±2.03)mg/L,(10.26±2.14)pg/ml,and(39.25±2.10)ng/ml in the control group,and the differences were statistically significant(P<0.05).Conclusion In the treatment of acute perforation of gastroduodenal ulcer,laparoscopic and open perforation repair can improve gastrointestinal function indexes,promote recovery,improve clinical inflammatory factors and maintain normal indexes.

关 键 词：腹腔镜穿孔修补术 开腹穿孔修补术 胃十二指肠溃疡急性穿孔 

分 类 号：R656.6[医药卫生—外科学]