植入式心脏起搏器单/双极起搏模式下回路阻抗研究及离体实验方案  

Study on Impedance of Implantable Cardiac Pacemaker in Unipolar/Bipolar Pacing Mode by in Vitro Experiment

作　　者：丁鼎 林开斌 黄冬[2] 郭心维 王延鹏[2] 李帅 李京波[2] 牛金海[1] DING Ding;LIN Kaibin;HUANG Dong;GUO Xinwei;WANG Yanpeng;LI Shuai;LI Jingbo;NIU Jinhai(School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai,200240;Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai,200233)

机构地区：[1]上海交通大学生物医学工程学院,上海市200240 [2]上海交通大学附属第六人民医院,上海市200233

出　　处：《中国医疗器械杂志》2022年第3期237-241,247,共6页Chinese Journal of Medical Instrumentation

基　　金：上海交通大学医工(理)交叉基金资助(YG2019ZDA10)。

摘　　要：心脏起搏器的单/双极起搏模式与其回路阻抗有关联,从而影响其电池使用寿命。该研究构建了心脏起搏器回路阻抗测试的离体实验方案,方案中使用NaCl溶液模拟人体血液环境,采取水浴的方式对实验环境温度进行控制。离体实验研究结果表明,单/双极模式的回路阻抗存在显著差异,在与临床人体参数相似的实验条件下,双极模式与单极模式的回路阻抗差值为120~200Ω。实验结果证实了临床上存在双极模式回路阻抗大于单极模式的现象,对临床心脏起搏器起搏模式的优化选择及起搏器功耗降低具有一定的参考意义。The unipolar/bipolar pacing mode of pacemaker is related to its circuit impedance, which affects the battery life. In this study, the in vitro experiment scheme of pacemaker circuit impedance test was constructed. The human blood environment was simulated by NaCl solution, and the experimental environment temperature was controlled by water bath. The results of in vitro experiments showed that under the experimental conditions similar to clinical human parameters, the difference between the circuit impedance of bipolar mode and unipolar mode is 120~200 Ω. The results of the in vitro experiment confirmed that the circuit impedance of bipolar circuit was larger than that of unipolar mode, which was found in clinical practice. The results of this study have reference value to the optimization of pacing mode and the reduction of pacemaker power consumption.

关 键 词：心脏起搏器 回路阻抗 单/双极起搏 离体实验 

分 类 号：R322.1[医药卫生—人体解剖和组织胚胎学] R197.39[医药卫生—基础医学]