维生素D在自身免疫性疾病及儿科应用中的研究进展  

Research Progress of Vitamin D in Autoimmune Diseases and Its Application in Pediatrics

作　　者：段俊彦 葛许华[2] DUAN Jun-yan;GE Xu-hua(Changzhou Second People’s Hospital Affiliated to Nanjing Medical University,Changzhou 213000,China;Department of Critical Medicine,Children’s Hospital of Nanjing Medical University,Nanjing 210008,China)

机构地区：[1]南京医科大学附属常州市第二人民医院,常州213000 [2]南京医科大学附属儿童医院重症医学科,南京210008

出　　处：《中国合理用药探索》2022年第4期1-6,共6页Chinese Journal of Rational Drug Use

摘　　要：维生素D(vitamin D)作为一种营养补充剂,是当下的研究热点之一。大量研究表明维生素D除了在骨代谢中的作用外,还具有显著的免疫调节特性。越来越多的研究表明维生素D缺乏与类风湿关节炎(RA)、多发性硬化(MS)等自身免疫性疾病相关。儿童生长发育迅速,对维生素D需求大,由于阳光暴露不足、摄入量不足等原因更容易引起维生素D缺乏。儿童维生素D缺乏与补充与各类急慢性疾病的关系应引起关注。本文将对以上内容一一进行阐述。As a nutritional supplement,vitamin D is a research hotspot at present.A large number of studies have shown that in addition to the role in bone metabolism,vitamin D also has significant immunomodulatory properties.More and more studies have shown that vitamin D deficiency is associated with autoimmune diseases such as rheumatoid arthritis(RA)and multiple sclerosis(MS).Children grow and develop rapidly and have a great demand for vitamin D.Due to insufficient sunlight exposure,insufficient intake and other reasons,they are more likely to cause vitamin D deficiency.More attention should be paid to the relationship between vitamin D deficiency and supplementation in children and various acute and chronic diseases.This article will elaborate on the above contents one by one.

关 键 词：维生素D 自身免疫性疾病 儿童 类固醇激素 类风湿关节炎 

分 类 号：R593[医药卫生—内科学]