运动干预对代谢异常患者代谢指标影响的实践评估  

The Effect of Exercise Intervention on Metabolic Indexes in Patients with Metabolic Abnormality

作　　者：邹煦[1] 谷荣娜 张晗[1] ZOU Xu;GU Rongna;ZHANG Han(Beijing Aerospace General Hospital Healthy Management Center,Beijing 100076,China)

机构地区：[1]北京航天总医院健康管理中心,北京100076

出　　处：《中国卒中杂志》2022年第5期491-496,共6页Chinese Journal of Stroke

基　　金：中国航天科技集团有限公司软课题研究(2018201)。

摘　　要：目的对代谢异常患者进行运动干预指导,评价其对患者代谢指标的影响,探索非药物干预措施预防心脑血管疾病的临床价值。方法本研究为前瞻性研究,一次性募集代谢异常患者,通过医学检查、体适能测试,开具个体化运动处方。通过微信群管理与现场运动指导相结合的方式进行运动干预,运动形式为有氧运动与力量训练结合,共12周。比较干预前后患者的BMI、体质量、腰围、血压、空腹血糖、血脂等代谢相关指标;计算并比较代谢综合征严重度积分(metabolic syndrome severity score,MSSS)、内脏脂肪指数(visceral adiposity index,VAI)干预前后变化。结果共招募109例代谢异常患者参与研究,完成12周干预者107例,其中男性43例(40.2%),女性64例(59.8%),平均年龄42.6±9.3岁。运动干预后空腹血糖[5.1(4.7~5.5)mmol/L vs.5.4(5.0~6.0)mmol/L,P<0.01]、LDL-C[2.8(2.4~3.6)mmol/L vs.3.2(2.7~3.7)mmol/L,P=0.04]、TC[4.8(4.3~5.4)mmol/L vs.5.6(4.6~5.8)mmol/L,P=0.01]、TG[1.3(0.9~1.7)mmol/L vs.1.5(1.1~2.3)mmol/L,P<0.01]等代谢性指标水平显著下降。MSSS[-1.8(-3.6~0.1)vs.-0.4(-2.7~1.5),P<0.01]、VAI[1.4(1.0~2.1)vs.1.8(1.2~3.0),P<0.01]较运动干预前均显著下降。结论制订个体化运动处方,通过现场与互联网线上指导、督促患者执行处方的运动干预方法可以作为改善代谢异常的治疗手段之一。Objective To evaluate the effect of exercise intervention on metabolic indexes of patients with metabolic abnormality,and explore the clinical value of non-drug intervention to prevent cardiocerebrovascular diseases.Methods This prospective study recruited the patients with metabolic abnormality at one time.According to medical examination results and physical fitness test,every patient was offered personalized exercise prescription.A total of 12-week exercise intervention was conducted through combining Wechat group management with on-site exercise guidance,with the exercise form of combining with aerobic exercise and strength training.The subjects’metabolic indexes such as BMI,body mass,waist circumference,blood pressure,fasting blood glucose,and blood lipid were compared before and after the intervention.Metabolic syndrome severity score(MSSS)and visceral adiposity index(VAI)were calculated and compared before and after the intervention.Results A total of 109 patients were included,of whom 107 patients completed the whole-course intervention,including 43 males(40.2%)and 64 females(59.8%),with an average age of 42.6±9.3years.After exercise intervention,metabolic indexes such as fasting blood glucose[5.1(4.7-5.5)mmol/L vs.5.4(5.0-6.0)mmol/L,P<0.01],LDL-C[2.8(2.4-3.6)mmol/L vs.3.2(2.7-3.7)mmol/L,P=0.04],TC[4.8(4.3-5.4)mmol/L vs.5.6(4.6-5.8)mmol/L,P=0.01],TG[1.3(0.9-1.7)mmol/L vs.1.5(1.1-2.3)mmol/L,P<0.01]decreased significantly.MSSS[-1.8(-3.6-0.1)vs.-0.4(-2.7-1.5),P<0.01]and VAI[1.4(1.0-2.1)vs.1.8(1.2-3.0),P<0.01]after exercise intervention were also decreased significantly compared to that before exercise intervention.Conclusions Making personalized exercise prescription and urging patients to implement the exercise intervention through on-site and network guidance,can be a kind of effective treatment means of improving metabolic abnormality.

关 键 词：运动干预 代谢综合征严重度积分 内脏脂肪指数 代谢异常 

分 类 号：R589[医药卫生—内分泌]