机构地区:[1]首都医科大学附属北京康复医院,北京100144
出 处:《中医药导报》2022年第4期39-44,共6页Guiding Journal of Traditional Chinese Medicine and Pharmacy
基 金:北京市残联项目(GFTC18AA0252/01);首都医科大学附属医院青年课题(2020-044)。
摘 要:目的:观察四君子汤加味联合弹力带训练治疗老年肌少症脾胃气虚证的疗效。方法:将100例老年肌少症脾胃气虚证患者随机分为对照组和治疗组,每组50例。对照组患者予老年肌少症的常规干预,治疗组患者在对照组基础上予四君子汤加味联合弹力带训练,均干预8周。比较治疗前后两组患者握力、四肢骨骼肌量指数(ASMI)、简易躯体活动能力评估表(SPPB)评分、营养指标[血清白蛋白(ALB)、前白蛋白(PA)和血清总蛋白(TP)]、中医证候评分,并评定疗效。结果:对照组脱落1例,49例患者完成研究,治疗组50例均完成研究;治疗组总有效率为92.00%(46/50),对照组总有效率为75.51%(37/49),治疗组疗效优于对照组,差异有统计学意义(P<0.05);干预后,两组患者握力、ASMI指数、SPPB评分及营养指标(ALB、PA和TP)均提高(P<0.05),且治疗组患者干预后握力、ASMI指数、SPPB评分及营养指标(ALB、PA和TP)均明显高于对照组,差异均有统计学意义(P<0.05);干预后,两组患者中医证候评分均降低(P<0.05),且治疗组患者干预后中医证候评分明显低于对照组(P<0.05)。结论:四君子汤加味联合弹力带训练治疗老年肌少症脾胃气虚证疗效明显,可有效提高患者的肌肉质量、肌肉功能,改善血清营养指标。Objective:To explore the effect of Sijunzi decoction combined with elastic band training on elderly sarcopenia with spleen and stomach deficiency syndrome.Methods:100 elderly sarcopenia patients with spleen and stomach deficiency syndrome were randomly divided into control group and observation group,with 50 cases in each group.The control group was given conventional interventions for elderly sarcopenia,and the observation group was given modified Sijunzi decoction combined with elastic band training on the basis of the control group.Both groups intervened for 8 weeks.The grip strength,limb skeletal muscle mass index(ASMI),short physical performance battery(SPPB)score,nutritional index[serum albumin(ALB),prealbumin(PA)and total serum protein(TP)]and TCM syndrome score of the two groups were compared before and after treatment,and the curative effect was evaluated.Results:One case fell off in the control group,49 cases in the control group completed the study and 50 cases in the observation group completed the study.The total effective rate was92.00%(46/50)in the observation group and 75.51%(37/49)in the control group.The curative effect of the observation group was better than that of the control group,the difference was statistically significant(P<0.05).After the intervention,the grip strength,ASMI index,SPPB score and nutritional indicators(ALB,PA,TP)of two groups all increased(P<0.05),and the above indicators of the observation group were higher than those of the control group,the differences were statistically significant(P<0.05).After the intervention,the TCM syndrome scores of the two groups were reduced(P<0.05),and the observation group was significantly lower than that of the control group(P<0.05).Conclusion:Modified Sijunzi decoction combined with elastic band training is effective in the treatment of elderly sarcopenia patients with spleen and stomach deficiency syndrome,which can effectively improve the muscle quality,muscle function and serum nutritional indicators.
关 键 词:肌少症 老年 脾胃气虚证 四君子汤加味 弹力带训练 肌肉质量 肌肉功能
分 类 号:R255.6[医药卫生—中医内科学]
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