云南不明原因猝死历史重病区村一起疑似云南不明原因猝死事件调查  

Field Epidemiological Investigation Investigation and analysis of two suspected Yunnan sudden unexplained death cases in a village with a history of Yunnan sudden unexplained death

作　　者：习严梅 雷普平 张正江 鲍建忠[5] 董毅[2] 马琳[2] 唐雪[2] 杨永鹏 孙梦遥 宋志忠[6] 王跃兵[2] Xi Yanmei;Lei Puping;Zhang Zhengjiang;Bao Jianzhong;Dong Yi;Ma Lin;Tang Xue;Yang Yongpeng;Sun Mengyao;Song Zhizhong;Wang Yuebing(School of Public Health,Dali University,Dali 671000,China;Yunnan Institute of Endemic Disease Control and Prevention,Yunnan Key Laboratory of Natural Foci Disease Prevention and Control Technology,Dali 671000,China;Department of Forensic Medicine of Kunming Medical University,Kunming 650500,China;Disease Control and Prevention Center of Dayao County,Dayao 675400,China;Disease Control and Prevention Center of Chuxiong Prefecture,Chuxiong 675000,China;Yunnan Center for Disease Control and Prevention,Kunming 650022,China)

机构地区：[1]大理大学公共卫生学院,大理671000 [2]云南省地方病防治所云南省自然疫源性疾病防控技术重点实验室,大理671000 [3]昆明医科大学法医学院,昆明650500 [4]云南省大姚县疾病预防控制中心,大姚675400 [5]云南省楚雄州疾病预防控制中心地方病防治科,楚雄675000 [6]云南省疾病预防控制中心,昆明650022

出　　处：《中华地方病学杂志》2022年第5期389-392,共4页Chinese Journal of Endemiology

基　　金：国家自然科学基金(81960573、81460285);徐建国院士工作站项目(2018IC155);陈义汉院士工作站建设基金(2019IC018);昆明医科大学创新团队(CXTD201803);云南省科技厅应用基础研究计划青年项目(2018FD111)。

摘　　要：目的探讨云南省大姚县2例疑似云南不明原因猝死病例的死亡原因。方法对2020年6月15-20日大姚县2例疑似云南不明原因猝死病例进行现场流行病学调查及尸体解剖,并采集血液及组织样本等进行常见毒物毒品定性分析。结果2例病例所在地区均为云南不明原因猝死历史重病区村,且死亡时间均发生在云南不明原因猝死的发病季节。2例病例间无血缘关系,死前均无明显异常症状,无特殊饮食,无农药和其他有毒化学药品接触史,常见毒物毒品检测结果均为阴性。尸体解剖病理检查结果显示,病例1死于冠心病突发急性心肌梗死致急性心功能障碍,病例2死于自发性蛛网膜下腔出血致中枢性呼吸循环功能衰竭。结论2例病例均通过尸体解剖排除云南不明原因猝死,并确定了死亡原因。提示在发生云南不明原因猝死病例时应尽快采取应急处置措施,积极通过开展尸体解剖,从病理学角度明确致死原因。Objective To explore the cause of death of 2 suspected Yunnan sudden unexplained death(YNSUD)cases in Dayao County,Yunnan Province.Methods The field epidemiological investigation and autopsy of 2 cases of YNSUD in Dayao County from June 15 to 20,2020 were conducted;and blood and tissue samples were collected for qualitative analysis of common poisons and drugs.Results The areas where the two cases were located were all seriously ill villages with a history of YNSUD,and the time of death occurred in the onset season of YNSUD.There was no blood relationship between the 2 cases,no obvious abnormal symptoms before death,no special diet,no history of exposure to pesticides and other toxic chemicals,and the test results of common poisons were all negative.Autopsy pathological examination results showed that case 1 died of acute cardiac dysfunction caused by sudden acute myocardial infarction of coronary heart disease,and case 2 died of central respiratory and circulatory failure caused by spontaneous subarachnoid hemorrhage.Conclusions The two cases are excluded from YNSUD through autopsy,and the cause of death is determined.It is suggested that emergency response should be taken as soon as possible for YNSUD cases,and autopsy should be actively carried out to clarify the cause of death from a pathological point of view.

关 键 词：猝死 尸体解剖 流行病学调查 

分 类 号：R541.78[医药卫生—心血管疾病]