厚朴麻黄汤随证加减治疗慢性支气管炎的效果分析  

Effect analysis of modified Houpu Mahuang Decoction in the treatment of chronic bronchitis

作　　者：王勃 WANG Bo(Northeast International Hospital,Shenyang 110016,China)

机构地区：[1]东北国际医院皇姑院区,110016

出　　处：《中国现代药物应用》2022年第7期147-149,共3页Chinese Journal of Modern Drug Application

摘　　要：目的研究慢性支气管炎患者采用厚朴麻黄汤随证加减治疗的临床效果。方法86例慢性支气管炎患者,根据治疗方案的不同分成对照组和治疗组,每组43例。对照组采用左氧氟沙星联合氨茶碱治疗,治疗组采用左氧氟沙星、氨茶碱、厚朴麻黄汤随证加减治疗。比较两组患者的药物不良反应发生情况,治疗效果,住院时间、呼吸功能指标复常时间、支气管炎症状消失时间,治疗前后呼吸功能相关指标[最大呼气流量占预计值的百分比(PEF%)、第1秒用力呼气容积占预计值的百分比(FEV1%)]水平。结果治疗组药物不良反应发生率4.7%低于对照组的20.9%,差异具有统计学意义(P<0.05)。治疗组治疗总有效率90.7%高于对照组的69.8%,差异具有统计学意义(P<0.05)。治疗组住院时间、呼吸功能指标复常时间、支气管炎症状消失时间分别为(6.06±1.41)、(4.86±2.25)、(3.23±1.84)d,短于对照组的(9.25±2.74)、(7.91±1.54)、(5.70±1.85)d,差异具有统计学意义(P<0.05)。治疗后,两组患者的PEF%、FEV1%均较本组治疗前升高,且治疗组患者的PEF%(88.96±4.72)%、FEV1%(84.27±5.20)%均高于对照组的(80.54±5.16)%、(76.61±6.35)%,差异均具有统计学意义(P<0.05)。结论慢性支气管炎患者采用厚朴麻黄汤随证加减治疗,能够减少药物不良反应,改善呼吸功能指标,缩短支气管炎症状消失、呼吸功能指标复常、住院时间,使病情治疗总有效率提高。Objective To study the clinical effect of modified Houpu Mahuang Decoction in the treatment of chronic bronchitis.Methods A total of 86 patients with chronic bronchitis were divided into control group and treatment group according to different treatment plans,with 43 cases in each group.The control group was treated with levofloxacin combined with aminophylline,and the treatment group was treated with levofloxacin,aminophylline,and modified Houpu Mahuang Decoction.Both groups were compared in terms of occurrence of adverse drug reactions,therapeutic effect,hospitalization time,recovery time of respiratory function indexes,disappearance time of bronchitis symptom,respiratory function related indexes[peak expiratory flow as a percentage of the predicted value(PEF%),forced expiratory volume in the 1st second as a percentage of the predicted value(FEV1%)]before and after treatment.Results The incidence of adverse drug reactions 4.7%in the treatment group was lower than 20.9%in the control group,and the difference was statistically significant(P<0.05).The total effective rate 90.7%of the treatment group was higher than 69.8%of the control group,and the difference was statistically significant(P<0.05).The hospitalization time,recovery time of respiratory function indexes,and disappearance time of bronchitis symptom in the treatment group were(6.06±1.41),(4.86±2.25),and(3.23±1.84)d,which were shorter than(9.25±2.74),(7.91±1.54),and(5.70±1.85)d in the control group,and the difference was statistically significant(P<0.05).After treatment,the PEF%and FEV1%of the two groups were higher than those of this group before treatment,and the PEF%(88.96±4.72)%and FEV1%(84.27±5.20)%of the treatment group were higher than(80.54±5.16)%and(76.61±6.35)%of the control group.All the differences were statistically significant(P<0.05).Conclusion Modified Houpu Mahuang Decoction for patients with chronic bronchitis can reduce adverse drug reactions,improve respiratory function indexes,shorten the disappearance time of bronchitis sy

关 键 词：慢性支气管炎 厚朴麻黄汤 随证加减 不良反应 治疗效果 呼吸功能 

分 类 号：R259[医药卫生—中西医结合]