基于聚类分析的糖尿病胃轻瘫中医证型分布研究  

Distribution of TCM Syndromes of Diabetic Gastroparesis Based on Cluster Analysis

作　　者：宋宁[1] 唐丽明[1] 杜红跃 袁红霞[2] SONG Ning;TANG Li-ming;DU Hong-yue;YUAN Hong-xia(Department of Traditional Chinese Medicine,Tianjin Nankai District Santan Hospital,Tianjin 300193,China;Baokang Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300000,China)

机构地区：[1]天津市南开区三潭医院中医科,天津300193 [2]天津中医药大学附属保康医院,天津300000

出　　处：《医学信息》2022年第11期97-101,共5页Journal of Medical Information

摘　　要：目的运用聚类分析的统计方法归纳糖尿病胃轻瘫(DGP)的中医证型分布,为DGP辨证论治提供理论指导。方法设计《糖尿病胃轻瘫中医证候要素提取表》,收集2018年11月-2019年10月我院及天津中医药大学附属保康医院256例DGP患者的中医症状、体征、舌象、脉象四诊信息,采用EXCEL进行频数分析及SPSS 22.0软件进行聚类分析,并结合临床专业知识归类总结DGP的中医证型。结果最终纳入252例患者,男137例,女115例,平均年龄(56.97±14.04)岁,平均病程(13.01±6.83)年;DGP的发病随年龄、病程的增加均有增长的趋势;DGP患者舌质以舌质红为主,脉象主要以滑、细脉为主,沉、弦脉次之;患者胃脘痞满、胃脘疼痛、食欲减退、食后腹胀、精神疲乏出现频率最高;聚类分析结果显示,聚为脾胃虚弱(寒)证、肝胃不和证、痰浊中阻证、湿热内蕴证、胃阴不足证、气滞血瘀证6组。结论采用聚类分析法将DGP分为脾胃虚弱(寒)证、肝胃不和证、胃阴不足证、湿热内蕴证、痰浊中阻证及气滞血瘀证6个证型,所得结果符合临床实际,辨证要点简明扼要,便于临床医师掌握。Objective To summarize the distribution of TCM syndrome types of diabetic gastroparesis(DGP)by using the statistical method of cluster analysis,and to provide theoretical guidance for the syndrome differentiation and treatment of DGP.Methods The"TCM Syndrome Elements Extraction Table"of diabetic gastroparesis was designed.The TCM symptoms,signs,tongue and pulse information of 256 patients with DGP in our hospital and Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine from November 2018 to October 2019 were collected.EXCEL was used for frequency analysis and SPSS 22.0 software was used for cluster analysis.Combined with clinical professional knowledge,the TCM syndrome types of DGP were classified and summarized.Results Among the 252 patients,137 were males and 115 were females,with an average age of(56.97±14.04)years and an average course of disease of(13.01±6.83)years.The incidence of DGP increased with age and course of disease;the tongue of patients with DGP was mainly red,and the pulse was mainly slippery pulse,small pulse,followed by sunken pulse and stringy pulse.Patients with epigastric fullness,epigastric pain,loss of appetite,abdominal distension after eating and mental fatigue had the highest frequency;the cluster analysis results showed that the patients were divided into six groups:spleen-stomach deficiency(cold)syndrome,liver-stomach disharmony syndrome,phlegm-turbidity syndrome,damp-heat syndrome,stomach-yin deficiency syndrome,and Qi-stagnation and blood stasis syndrome.Conclusion DGP is divided into six syndromes by cluster analysis,namely spleen-stomach deficiency(cold)syndrome,liver-stomach disharmony syndrome,phlegm-turbidity syndrome,damp-heat syndrome,stomach-yin deficiency syndrome,and Qi-stagnation and blood stasis syndrome The results are consistent with clinical practice,and the key points of syndrome differentiation are concise and easy to be mastered by clinicians.

关 键 词：糖尿病胃轻瘫 中医证型 体征 舌象 脉象 

分 类 号：R587.2[医药卫生—内分泌]