盐酸利托君结合硫酸镁在早产胎膜早破中的应用及对妊娠时间的影响  

Application of ritodrine hydrochloride combined with magnesium sulfate in preterm premature rupture of membranes and its effect on pregnancy time

作　　者：陈鑫 肖琳[1] 靳健美 CHEN Xin;XIAO Lin;JIN Jianmei(Department of Obstetrics and Gynecology,Dazhou Integrated Traditional Chinese and Western Medicine Hospital in Sichuan Province,Dazhou635000,China)

机构地区：[1]四川省达州市中西医结合医院妇产科,四川达州635000

出　　处：《中国现代医生》2022年第15期92-95,共4页China Modern Doctor

摘　　要：目的 探讨盐酸利托君结合硫酸镁在早产胎膜早破中的应用及对妊娠时间的影响。方法 选取2019年6月至2021年1月四川省达州市中西医结合医院收治的存在早产胎膜早破征兆的孕产妇100例,依照治疗方案的差异分为两组,每组各50例。对照组应用硫酸镁治疗,研究组应用盐酸利托君结合硫酸镁治疗。比较两组的临床治疗效果、临床指标状况及分娩结局。结果 研究组的治疗有效率高于对照组(P<0.05);研究组延长妊娠时间为(19.77±1.25)d,多于对照组的(6.15±2.16)d;研究组的治疗时间[(4.05±1.01)d]及宫缩抑制时间[(2.49±0.78)h]少于对照组的[(6.52±1.30)d]及[(4.26±1.23)h](P<0.05);研究组的足月分娩率(82.0%)及胎儿存活率(100.0%)均高于对照组[(58.0%)、(94.0%)],研究组的胎儿早产率(18.0%)低于对照组(42.0%)(P<0.05);研究组不良反应发生率为4.0%,低于对照组的18.0%(P<0.05);研究组的SAS评分为(30.25±3.08)分,低于对照组的(46.41±4.62)分;研究组的产后出血量为(201.34±36.24)ml,少于对照组的(235.12±42.25)ml(P<0.05)。结论 应用盐酸利托君结合硫酸镁治疗早产胎膜早破,可提升疗效,延长孕妇的妊娠时间,提升分娩结局,值得应用。Objective To investigate the application of ritodrine hydrochloride combined with magnesium sulfate in preterm premature rupture of membranes and its effect on pregnancy time. Methods A total of 100 pregnant women with signs of preterm premature rupture of membranes treated in our hospital from June 2019 to January 2021 were selected. With clinical data collected, they were divided into two groups, with 50 cases in each group. The control group received magnesium sulfate, while the study group received ritodrine hydrochloride combined with magnesium sulfate. The clinical treatment effects, clinical indicators, and delivery outcomes were compared between the two groups.Results The effective rate of treatment in the study group was higher than that in the control group(P< 0.05);the prolonged pregnancy time in the study group was(19.77±1.25)d,which was longer than that in the control group(6.15±2.16)d, while the treatment time [(4.05±1.01)d] and the uterine contraction inhibition time [(2.49 ±0.78)h] of the study group were shorter than those of the control group [(6.52±1.30)]d,[(4.26±1.23)h](P<0.05);the probability of full-term delivery(82.0%) and the probability of fetal survival(100.0%) in the study group were higher than those in the control group(58.0%,94.0%), while the preterm birth rate(18.0%) in the study group was lower than that in the control group(42.0%)(P<0.05);the proportion of adverse reactions in the study group(4.0%) was lower than that in the control group(18.0%)(P <0.05);the SAS score of the study group [(30.25 ±3.08) points] was lower than that of the control group(46.41±4.62)points, while the postpartum hemorrhage in the study group [(201.34 ±36.24) ml] was less than that in the control group [(235.12±42.25) ml](P<0.05). Conclusion The application of ritodrine hydrochloride combined with magnesium sulfate in the treatment of premature rupture of membranes can improve the curative effect, prolong the pregnancy time and improve the delivery outcome. Therefore, it is worth applying.

关 键 词：盐酸利托君 硫酸镁 早产胎膜早破 妊娠时间 

分 类 号：R714.2[医药卫生—妇产科学]