盐酸帕罗西汀联合还少胶囊治疗长期病理性遗精的个案报道  

Treatment on long-term pathological spermatorrhea by paroxetine hydrochloride combined with Huanshao Capsule:a case report

作　　者：赵玉[1,2] 欧阳斌 孙远[1,2] 李重 陈少峰 耿强[1,2] ZHAO Yu;OUYANG Bin;SUN Yuan;LI Zhong;CHEN Shaofeng;GENG Qiang(Department of Andrology,First Affiliated Hospial of Tianjin Universtiy of Tradional Chinese Medicine,Tianjin 300193,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300193,China)

机构地区：[1]天津中医药大学第一附属医院男科,天津300193 [2]国家中医针灸临床医学研究中心,天津300193

出　　处：《中国性科学》2022年第5期134-137,共4页Chinese Journal of Human Sexuality

基　　金：天津市卫生和计划生育委员会中西医结合课题(2017129)。

摘　　要：通过回顾性分析1例长期病理性遗精患者的诊治过程及查阅相关文献资料探讨病理性遗精的治疗方案及该病可能的发生机制。该患者在口服盐酸帕罗西汀及还少胶囊后,夜间频繁遗精的症状得到有效控制。针对病理性遗精,可尝试采用盐酸帕罗西汀结合还少胶囊进行治疗。推测病理性遗精发生的潜在机制是人体内5-羟色胺1A(5-HT_(1A))及5-羟色胺2C(5-HT_(2C))受体平衡遭到破坏,而盐酸帕罗西汀可恢复此平衡,从而减少遗精的发生,同时结合具有补肾健脾功效的还少胶囊,可成功控制遗精症状,改善患者生活质量。We explored treatment plan and possible mechanism of pathological spermatorrhea through a retrospective analysis of the diagnosis and treatment process of 1 patient with long-term pathological spermatorrhea and comprehensive review of relevant literature.The patient′s symptoms of frequent nocturnal spermatorrhea were effectively controlled after oral administration of paroxetine hydrochloride and Huanshao Capsule.For pathological spermatorrhea,paroxetine hydrochloride combined with Huanshao Capsule can be used for treatment.We speculated that the potential mechanism of pathological spermatorrhea is the broken of the balance between 5-serotonin receptor 1 A(5-HT_(1A))and 5-serotonin receptor 2 C(5-HT_(2C))in vivo,and paroxetine hydrochloride can restore this balance.As a result,the occurrence of spermatorrhea reduced.Meanwhile,combining with Huanshao Capsule which can tonify kidney and spleen,can successfully controll spermatorrhea and improved quality of life of the patients.

关 键 词：病理性遗精 盐酸帕罗西汀 还少胶囊 机制探讨 

分 类 号：R698[医药卫生—泌尿科学]